Nursing REPLICA O-ASL FROSINONE UMBERTO I

General Pharmacology Pharmacokinetics: Routes of drug administration and their different characteristics. Mechanisms and principles that regulate the absorption, distribution, metabolism and elimination of drugs. Clinical pharmacokinetics: Bioavailability, volume of distribution, clearance, half-life, steady state, loading dose. Pharmacodynamics: General principles of action of drugs. Drug-receptor interaction. Agonists and antagonists. Dose-response curves and other pharmacodynamic parameters. Characteristics of the main receptors (receptors for neurotransmitters, channel receptors, intracellular receptors. Pumps and transporters, enzymes, receptors for chemotherapy), tolerance, therapeutic index. Clinical Pharmacology Factors that influence the action of drugs: physiological states, age, genetic factors, pathological states. Adverse reactions and drug abuse. Pharmacovigilance. Interactions between drugs Special Pharmacology Autonomic Nervous System Drugs: SNS and SNPS, Sympathomimetics and Sympatholytics. Cardiovascular System Drugs: Calcium antagonists, ACEs, diuretics; nitrates; clotting drugs Drugs active on the Central Nervous System: Anxiolytics, opioid analgesics and antipsychotics

To understand the contents of the Pharmacology module and achieve the learning objectives, the student must know the elements of chemistry and biochemistry, physics and biology, as well as histology, anatomy and physiology.

Conforti, Cuzzolin, Leone, Moretti, Pignataro, Taglialatela, Vanzetta Farmacologia per le professioni sanitarie SORBONA Idelson-Gnocchi Di Giulio, A Gorio, S Carelli, SG Cella e F Scaglione Farmacologia generale e speciale Piccin Amico-Roxas, Caputi, Del Tacca Compendio di Farmacologia generale e speciale UTET

Frontal lessons. The lessons will begin with the illustration of a clinical case and will end with tests to verify the understanding of the subject matter.

In order to be able to take the exam related to the specific integrated course it is necessary to have documented the presence in the classroom of at least 66% of the hours corresponding to the credits assigned to the integrated course.

To Pass the test student must obtain a note of 18/30 for each subject of the integrated teach. Student must possess a sufficient knowledge of the program To obtain a note of 30/30 with distinction student must possess an excellent knowledge of the whole program using a correct terminology to expose the topics. The oral examination of pharmacology must evaluate the preparation of the candidate in the first part of General Pharmacology and in the second part of Special Pharmacology. Therefore, the exam consists of two questions. The exam begins with a question on special pharmacology and then takes inspiration from the topic to explore an aspect of general pharmacology.

Frontal lessons. The lessons will begin with the illustration of a clinical case and will end with tests to verify the understanding of the subject matter.