Biomedical Laboratory techniques REPLICA B - ROMA AZIENDA S.CAMILLO FORLANINI

.Principles of Pharmacokinetics: absorption, distribution, metabolism, elimination of drugs. •Principles of Pharmacodynamics: Concept of receptor. Main receptor classes: G-protein coupled receptors, tyrosine kinase receptors, channel receptors. Diseases related to alteration of receptors or their signal transduction . Hints at mechanisms of regulation of receptor activity. • Protein electrophoresis and western blotting for the study of receptors and signal transduction. • Study techniques in pharmacology: "in vivo" and "in vitro" models. Cell cultures. • Transfection techniques and cDNA production by bacterial transformation. • Antibiotic resistance. • Drug development: the pre-clinical and clinical trials.

Anna Maria DI GIULIO- Alfredo GORIO-Stephana CARELLI- Silvano Gabriele CELLA- Francesco SCAGLIONE FARMACOLOGIA GENERALE E SPECIALE Per le lauree sanitarie Edizioni PICCIN - Bertram Katzung, Marieke Kruidering-Hall, Anthony J. Trevor FARMACOLOGIA Compendio e quesiti a scelta multipla Edizioni PICCIN - Richard D. Howland, Mary J. Micek LE BASI DELLA FARMACOLOGIA Edizioni ZANICHELLI