Nursing REPLICA ASL ROMA 2

Difference between emergency and urgency Medicines in cardiac emergencies: cardiac arrest ADRENALINE and catecholamines, notes on the adrenergic receptor (synthesis of noradrenaline, uptake in the vesicles and storage, release of the neurotransmitter, binding to the receptor, removal of noradrenaline, metabolism), receptor specificity, direct, indirect and mixed agonists, main effects on the body FIBRINOLYTIC DRUGS the coagulation cascade, fibrinogen activation, ALTEPLASIS Intraosseous route of administration acute coronary syndromes MORPHINE ACETYLSALICYLIC ACID synthesis of prostaglandins and leukotrienes, metabolism of acetylsalicylic acid, mechanism of action of clopidogrel and other antiplatelet agents NITROGLYCERIN and organic nitrates ANTICOAGULANTS unfractionated heparins and EPBM, differences FIBRINOLITHICS in the reperfusion strategy ANTIPERTENSIVES (beta blockers, calcium channel blockers, ACE inhibitors, angiotensin receptor blockers, aldosterone antagonists) OXYGEN THERAPY Hypertensive emergency, differences between transient hypertension, acute hypertensive episode, hypertensive urgency, hypertensive emergency and treatment NITROGLYCERIN, LABETALOL, FENOLDOPAM, NIFEDIPINE arrhythmias Antiarrhythmic drugs to be used according to the type of arrhythmia, class I, Ia (disopyramide, procainamide, quinidine), Ib (lidocaine, mexiletine), Ic (flecainide, propafenone) class II (atenolol, bisoprolol, carvedilol, esmolol, metoprolol, nadolol, propranolol, timolol), class III (sotalol, bretilium, amiodarone), class IV (diltiazem, verapamil); adenosine and digoxin. Drugs in atrial fibrillation Various types of shock (hypovolemic, distributive, cardiogenic, obstructive) and treatment, lactated ringer and acetate ringer. Medicines in respiratory emergencies: bronchial asthma, treatment of acute crises: Inhaled bronchodilators beta-2-agonists, adrenaline, terbutaline; anticholinergics: the muscarinic receptor, (synthesis of acetylcholine, uptake in the vesicles, release of the neurotransmitter, binding to the receptor, degradation of acetylcholine, reuse of choline) ipratropium; systemic corticosteroids, mechanism of action, effects, adverse events (methylprednisolone, prednisolone, prednisone); omalizumab Exacerbated COPD and therapy: bronchodilators (beta agonists salbutamol, fenoterol, terbutaline; anticholinergics ipratropium; corticosteroids, prednisone, methylprednisolone; antibiotics, trimetroprim / sulfamethoxazole, amoxicillin, doxycycline, azithromycin) Rapid sequence intubation the 6 P rule (preparation, pre-oxygenation, pre-treatment, paralysis and sedation, passage of the tube and positioning control, post intubation) and drugs used in the various phases. Depolarizing and non-depolarizing muscle relaxant drugs, sugammadex INTOXICATIONS definition of adverse reaction and toxicological incidents, DEAD decontamination, enhanced elimination, antidotes, disposition, antidotes (priority and minimum stocks), poison control center, focus on acetylcysteine, flumazenil, naloxone Anaphylaxis and drugs used: adrenaline, crystalloids (differences with colloids), vasoconstrictors, antihistamines, beta agonists, method for determining the volume of fluid required for resuscitation. Medicines in CNS emergencies: stroke (ischemic and haemorrhagic): tissue plasminogen activator (alteplase), antiplatelet agents (acetylsalicylic acid, clopidogrel, dipyridamole), anticoagulants (heparin), antihypertensives (nicardipine, labetalol, clevidipine) status epilepticus: diazepam, midazolam, lorazepam, mechanism of action and receptor for benzodiazepines and barbiturates, phenytoin OXYGEN THERAPY FiO2, most used devices and flow ranges: Goggles or nasal cannula, Simple mask, Mask with reservoir, Venturi mask, Hi-flow nasal cannula, Oximask CALCULATIONS TO KNOW FOR PROPER ADMINISTRATION OF DRUGS exercises in the classroom, IMPORTANCE IN KNOWING HOW TO PERFECTLY RECOGNIZE THE CONCENTRATION OF A DRUG TO AVOID ADMINISTRATION ERRORS

Pharmacotherapy-a pathophysiologic approach (Dipiro, Talbert, Yee et al.) ed. Mc Graw Hill Medical Tenth Edition; Le basi farmacologiche della terapia. Il manuale (Laurence L. Brunton, Randa Hilal-Dandan; Zanichelli, 2 ed.) ABC della terapia in emergenza-urgenze (S. Grifoni) ed. Piccin 1 ed. Farmacologia clinica e Terapia sistematica in Medicina Critica e d' Emergenza – Urgenza (di Zanza – Longhitano) Idelson-Gnocchi 1 ed.