INTERPRETATION OF MASS SPECTRA OF MODEL DRUGS
Course objectives
General expected learning outcomes The general expected learning outcome of this 2 CFU course is to provide a thorough knowledge of the ChemDraw software for the design of organic molecules and the prediction of the most frequent molecular fragmentations that occur in a mass spectrometer (use of the ChemDraw "mass fragmentation" command). The acquired knowledge will be applied by the students to interpret the ESI mass spectra of model drugs (offered by the teacher), by attributing the different peaks in the spectrum to specific fragments produced within the ionization source. Specific expected learning outcomes 1. Knowledge and understanding At the end of the course the student has a thorough knowledge of the ChemDraw software for the design of organic molecules and the prediction of the most frequent molecular fragmentations that occur in a mass spectrometer (use of the ChemDraw "mass fragmentation" command). 2. Applying knowledge and understanding At the end of the course the student is able to interpret an ESI mass spectrum of a model drug and to attribute the different peaks present in the spectrum to specific fragments produced within the ionization source. 3. Making judgements At the end of the course the student is able to independently decide which analytical method is more useful to solve a particular trouble he may meet in the working field, from the characterization of new active ingredients of therapeutic interest to the production and quality control of the drug. 4. Communication skills At the end of the course the student has the ability to communicate the knowledge he has learned during the course to the outside world, both with regard to the scientific community and the world of work. In particular, he/she must be able to present information relating to mass spectrometry and its possible application to the field of drugs in a clear and straight way. 5. Learning skills The student who has passed the exam is able to continue the study by reading the most recent articles published in the literature that the teacher makes available to him/her on the e-learning platform. He/she is also able to check specific databases in the field of drugs.
- Lesson codeAAF2376
- Academic year2025/2026
- CourseIndustrial pharmacy REPLICA LATINA
- CurriculumCurriculum unico
- Year5th year
- Semester1st semester
- CFU2