Medicine and Surgery

Pathophysiology of the immune system. Clinical and laboratory diagnostics of immune system diseases and allergic disorders. Primary and secondary immunodeficiencies. Connective tissue diseases (systemic lupus erythematosus, antiphospholipid syndrome, Sjögren’s syndrome, systemic sclerosis, polymyositis/dermatomyositis). Main organ-specific autoimmune diseases (autoimmune hepatitis, primary biliary cirrhosis, autoimmune gastropathies). Sarcoidosis. Vasculitis: general concepts, classification, clinical features, and diagnosis of the main forms, including: Giant cell arteritis (temporal arteritis); Takayasu arteritis; Polyarteritis nodosa; Kawasaki disease; Granulomatosis with polyangiitis (Wegener’s granulomatosis); Eosinophilic granulomatosis with polyangiitis (Churg–Strauss syndrome); Microscopic polyangiitis; Schönlein–Henoch purpura; Cryoglobulinemic vasculitis; Behçet’s disease. Allergic diseases: general concepts; IgE-mediated and non–IgE-mediated allergic disorders; pseudoallergies; allergologic diagnostics; food allergies; atopic dermatitis; urticaria–angioedema syndrome; allergic rhinoconjunctivitis; allergic asthma; allergic contact dermatitis; hymenoptera venom allergy; drug allergies; severe allergic reactions (anaphylactic and anaphylactoid reactions, erythema multiforme, Stevens–Johnson syndrome, CREST syndrome). Therapy of allergic diseases; specific desensitization immunotherapy.