THREE-DIMENSIONAL MODELING

Course objectives

Know and understand pharmacokynetics, pharmacodynamics and the mechanisms of toxicity of drugs Know how to make, on the basis of knowledge of pharmacokynetics and pharmacodynamics, an evaluation of the drug and to make a reasoned choice of the method and duration of administration Be aware of the factors that influence pharmacological effects, adverse reactions and the interaction between drugs, as well as the ethical and socio-economic implications inherent in the prescription of drugs.

Channel 1
VALERIA MARIA GLORIA BRUNO Lecturers' profile

Program - Frequency - Exams

Course program
PHARMACOLOGY AND TOXICOLOGY I: Origin and development of drugs. Clinical trials of drugs. Toxicology: general principles. Pharmacovigilance: objectives and methodology. Pharmacodynamics. G-protein-coupled receptors, channel receptors, intracellular receptors, ion channels. GABAergic, serotonergic, noradrenergic, dopaminergic, histaminergic, cholinergic transmission. Drug routes of administration. Pharmacokinetics: absorption, distribution, metabolism and excretion. Pharmacokinetic parameters. Equivalent drugs and biosimilars. Variability of drug effects based on genetics, physiological and pathological conditions, age and gender. Autonomic Nervous System Pharmacology. Medications in bronchial asthma and COPD. Drugs for peptic ulcers; antiemetics and prokinetics. Pharmacology of inflammatory processes: NSAIDs; antileukotrienic drugs; corticosteroids; antihistamines. Pharmacology of the endocrine system: intracellular receptors and drugs acting on them. Antibiotics: classification and resistance. Fluoroquinolones, Macrolides, Beta-lactams.
Prerequisites
None
Books
Goodman & Gilman, Le basi farmacologiche della terapia, XIII Ed, 2019, L. Brunton, R. Hilal Dandan, C. Knollmann Farmacologia. Principi di base e applicazioni terapeutiche, IV Ed., F. Rossi, V. Cuomo, C. Riccardi, III Ed, 2019
Teaching mode
Oral examination
Frequency
The student must be present in at least 70% of the lessons
Exam mode
To Pass the test student must obtain a note of 18/30 for each subject of the integrated teach. Student must possess a sufficient knowledge of the program. To obtain a note of 30/30 with distinction student must possess an excellent knowledge of the whole program using a correct terminology to expose the topics.
Lesson mode
Oral examination
  • Academic year2025/2026
  • CourseMedicine and Surgery
  • CurriculumSingle curriculum
  • Year4th year
  • Semester2nd semester
  • SSDBIO/14
  • CFU3