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The course aims to define, as specific goal (knowledge and understanding), the interaction between concepts of sustainability and safety, in terms of the development of risk assessment models that integrate the definition of the ethical-legal criterion - social-economic-technical "acceptability" of the residual risk. Soft skills enrich knowledge and understanding of these concepts by means of the production strategies' analysis (in terms of goods and services), the use of innovative technologies applied to territorial system, the ethics of technical safety as the only sustainable choice. According to the transversal nature of risk concept and safety, applications concerning the territorial vulnerability with regard to critical infrastructures and complex systems and the impact of accidents will be presented for the integrated risk analysis model related to the management of critical events (natural or anthropogenic). The aim of this course is, therefore, to mapp a theoretical conceptual scheme to identify synthetic indicator strating from territorial risk components by means of holistic representation model, according to which this dimension is positively correlated to factors of territorial vulnerability and negatively to factors of resilience. We intend to describe the local system in its specific dimensions (defined as cindinic hyperspace) to investigate how exposure to risk is determined by environmental and anthropogenic factors. The analysis of the technical literature, of the economic, societal and territorial factors, relevant from the point of view of the exposure of the territory to the risk of a disturbing condition, allows to do the map of territorial resilience on a regional scale. The logical, ethical-axiological, epistemic-statistical criteria will allow the components identified to be traced back to the macro-categories "vulnerability" and "resilience" (by identifying attributes that involve structural heterogeneity, redundancy, availability of resources, adaptation of the territorial system). Knowledge and understanding (ref. section A4.b.2 SUA document): after passing the exam, the students will be able to deal with issues related to safety management both from the point of view of territorial risk analysis and the managing of safety solutions. Applying knowledge and understanding (ref. section A4.b.2 SUA document): after passing the exam, the students will be able to make design choices with regard to the safety of territorial systems. After passing the exam, the students will acquire the ability to make judgments with particular regard (ref. section A4.c SUA document) to “assess the safety conditions in service activities and in industrial and civil infrastructures (industrial plants and process, construction site) by focusing the design, operational and procedural strategies necessary to guarantee an appropriate level of safety and to verify the acceptability of residual risk ". The required learning skills will contribute to the process of self-learning (learning skills) that will continue related to the expected professional skills of the learning process, as well as to the required specific issues (ref. A4.c SUA document). Individual and group project work will also contribute to the student's development of self-learning skills also related to the ability to formulate critical judgments and assessments (making judgments) starting from limited or incomplete information (ref. section A4.c SUA document "assessments and analysis of design projects and logistical-operational solutions in construction sites and workplaces, to verify the compliance with the general safety requirements of workers as well as safeguarding the integrity of the environment"). Keywords: territorial resilience, territorial risks, management and planning of ordinary and emergency conditions