Medicine and Surgery

see Prof Lotti

Students must have acquired the knowledge relating to the previous course years and must take the exam based on the preparatory qualifications of the previous exams of the course

General Pathology and General Physiopathology (Pontieri-Russo-Frati)

frontal lessons

compulsory attendance, attendance will be recorded using signature sheets and once the attendance threshold is reached (75% of the hours of scheduled lessons) the obligation to attend is considered fulfilled.

accurate evaluation by oral interview

lessons with slides

A basic knowledge of biochemistry, biology and genetics, human histology and embryology, microbiology, human anatomy and physiology is required. To take the final exam (including the I and II semester), the student must have passed all the exams of the I and II years and Human Physiology.

mandatory

oral examination

lectures

• • Oncology. Phenotypic changes: metaplasia, dysplasia, anaplasia. Precancerous lesions. Introduction to oncology: molecular mechanisms of neoplastic transformation. Definition of tumor. Morphological and biochemical characteristics of the neoplastic cell. Physical, chemical, viral,nutritional and hormonal carcinogenesis. Criteria for tumor classification: classification according to biological behavior, histogenetic classification of tumors, clinicopathological classification of tumors (staging, grading), molecular classification of neoplasms. Oncogenes and their mechanisms of activation. Oncosuppressor genes. Cancer stem cells. Stages of the neoplastic process: initiation, promotion and progression (invasion, metastasis, angiogenesis). Tumor microenvironment. Pathophysiology of cell replication and differentiation in tumors. Genomic instability. Epigenetics and tumors. Metabolism and tumors. Hereditary tumors. Tumors of the blood. Biological basis of antineoplastic therapy. • General pathophysiology General pathophysiology of metabolism (amino acids, lipids, carbohydrates, purine and pyrimidine bases). General pathophysiology of hydro-electrolyte turnover and acid-base balance, Shock, Edema Pathophysiology of hypertension and atherosclerosis Pathophysiology of renal, respiratory, cardiac, digestive function. Pathophysiology of liver and biliary tract, dyslipidemia Pathophysiology of nutrition: obesity, nutraceuticals, celiac disease, food intolerances Pathophysiology of blood, hematopoietic organs and hemostasis. Endocrine pathophysiology. Pathophysiology of the integrated hypothalamic-pituitary system. Pathophysiology of the thyroid gland. Pathophysiology of multiple endocrine neoplasms (MEN). Pathophysiology of the adrenal gland. Pathophysiology of diabetes mellitus.

A basic knowledge of biochemistry, biology and genetics, human histology and embryology, microbiology, human anatomy and physiology is required. To take the final exam (including the I and II semester), the student must have passed all the exams of the I and II years and Human Physiology. It is not necessary to have completed the Human Physiology exam to take the eligibility (only I semester topics).

Pontieri – Mainiero – Misasi – Sorice. Patologia generale e fisiopatologia generale – Volumi 1 e 2 ed. Piccin, VI edizione 2018 Robbins e Cotran. Le basi patologiche delle malattie. Patologia generale cofanetto (ed. 2021) ed. EDRA

Mandatory

Oral examination

Frontal lectures

• Oncology. Phenotypic changes: metaplasia, dysplasia, anaplasia. Precancerous lesions. Introduction to oncology: molecular mechanisms of neoplastic transformation. Definition of tumor. Morphological and biochemical characteristics of the neoplastic cell. Physical, chemical, viral,nutritional and hormonal carcinogenesis. Criteria for tumor classification: classification according to biological behavior, histogenetic classification of tumors, clinicopathological classification of tumors (staging, grading), molecular classification of neoplasms. Oncogenes and their mechanisms of activation. Oncosuppressor genes. Cancer stem cells. Stages of the neoplastic process: initiation, promotion and progression (invasion, metastasis, angiogenesis). Tumor microenvironment. Pathophysiology of cell replication and differentiation in tumors. Genomic instability. Epigenetics and tumors. Metabolism and tumors. Hereditary tumors. Tumors of the blood. Biological basis of antineoplastic therapy. • General pathophysiology General pathophysiology of hydro-electrolyte turnover and acid-base balance, Shock, Edema Pathophysiology of hypertension and atherosclerosis Pathophysiology of renal, respiratory, cardiac, digestive function. Pathophysiology of liver and biliary tract, dyslipidemia Pathophysiology of nutrition: obesity, nutraceuticals, celiac disease, food intolerances Pathophysiology of blood, hematopoietic organs and hemostasis. Endocrine pathophysiology. Pathophysiology of the integrated hypothalamic-pituitary system. Pathophysiology of the thyroid gland. Pathophysiology of multiple endocrine neoplasms (MEN). Pathophysiology of the adrenal gland. Pathophysiology of diabetes mellitus. Phatophysiology of the metabolism of purines. Gout. Phatophysiology of the metabolism of carbohydrates. Phatophysiology of the metabolism of proteins. Phatophysiology of the metabolism of calcium. Phatophysiology of the parathyroid glands.

A basic knowledge of biochemistry, biology and genetics, human histology and embryology, microbiology, human anatomy and physiology is required. To take the final exam (including the I and II semester), the student must have passed all the exams of the I and II years and Human Physiology.

Pontieri-Russo-Frati, Patologia Generale, Ed Piccin Robbins and Cotran, Pathologic basis of disease, Elsevier Saunders Rubin's Pathology, Clinicopathologic Foundations of Medicine, Rubin and Stryer, Lippincott Raven

Ex cathedra lessons and telematic lessons with Google Zoom. Power Point lessons in Moodle

67% of the presence is requested fro the exam.

Two different combinations for oral exam with open answers are proposed in presence in the classroom: a) to take a first oral exam which exonerates from the program of the first semester, followed by a second oral exam on the program of the second semester b) to take a single oral exam on the entire program of the first and second semesters

Ex cathedra lessons. Power Point lessons in Moodle.

• Oncology. Phenotypic changes: metaplasia, dysplasia, anaplasia. Precancerous lesions. Introduction to oncology: molecular mechanisms of neoplastic transformation. Definition of tumor. Morphological and biochemical characteristics of the neoplastic cell. Physical, chemical, viral,nutritional and hormonal carcinogenesis. Criteria for tumor classification: classification according to biological behavior, histogenetic classification of tumors, clinicopathological classification of tumors (staging, grading), molecular classification of neoplasms. Oncogenes and their mechanisms of activation. Oncosuppressor genes. Cancer stem cells. Stages of the neoplastic process: initiation, promotion and progression (invasion, metastasis, angiogenesis). Tumor microenvironment. Pathophysiology of cell replication and differentiation in tumors. Genomic instability. Epigenetics and tumors. Metabolism and tumors. Hereditary tumors. Tumors of the blood. Biological basis of antineoplastic therapy. • General pathophysiology General pathophysiology of metabolism (amino acids, lipids, carbohydrates, purine and pyrimidine bases). General pathophysiology of hydro-electrolyte turnover and acid-base balance, Shock, Edema Pathophysiology of hypertension and atherosclerosis Pathophysiology of renal, respiratory, cardiac, digestive function. Pathophysiology of liver and biliary tract, dyslipidemia Pathophysiology of nutrition: obesity, nutraceuticals, celiac disease, food intolerances Pathophysiology of blood, hematopoietic organs and hemostasis. Endocrine pathophysiology. Pathophysiology of the integrated hypothalamic-pituitary system. Pathophysiology of the thyroid gland. Pathophysiology of multiple endocrine neoplasms (MEN). Pathophysiology of the adrenal gland. Pathophysiology of diabetes mellitus.

A basic knowledge of biochemistry, biology and genetics, human histology and embryology, microbiology, human anatomy and physiology is required. To take the final exam (including the I and II semester), the student must have passed all the exams of the I and II years and Human Physiology.

Pontieri – Mainiero – Misasi – Sorice. Patologia generale e fisiopatologia generale – Volumi 1 e 2 ed. Piccin, VI edizione 2018 Robbins e Cotran. Le basi patologiche delle malattie. Patologia generale cofanetto (ed. 2021) ed. EDRA

attendance is mandatory

oral test on topics covered during lectures

frontal lectures