Course program
Clinical manifestations of kidney diseases: Nephritic and Nephrotic syndroms, Isolated Urinary
Abnormalities, Acute renal failure, Chronic renal failure, Arterial hypertension, hydro-electrolytic disorders
Diagnostic tools in kidney diseases: Study of renal function. Laboratory tests (urine and urinary sediment
examination, clinical chemistry, microbiology, molecular biology), Radiology and ultrasonography, Renal
biopsy.
Acute Kidney Injury: Pre-renal, Renal and Post-renal. Definition, classification, etiology, pathogenesis,
clinical picture, diagnosis and differential diagnosis.
Chronic kidney disease: Definition and classification. Etiology and pathophysiology, clinical picture and
diagnosis of CKD.
Uremic syndrome:
hydroelectrolyte disorders: hypo- and hypernatremia, metabolic acidosis and alkalosis, IPO-hyperkalemia
CKD-MBD: Mineral Bone disorders
Cardiovascular and pulmonary disorders. Haematological and immune disorders. Neuromuscular,
endocrine, gastrointestinal, dermatological disorders in Uremic syndrome.
Renal function replacement therapies:
Hemodialysis: physical principles, therapeutic indications and clinical picture of the patient on
hemodialysis.
Peritoneal dialysis: physical principles, therapeutic indications and clinical picture of the patient on
peritoneal dialysis
Kidney transplantation: selection criteria of the recipient patient; organ donation and donor selection;
immunosuppression; clinical picture of the transplanted patient, marginal donor
Glomerulonephritis:
Pathogenetic mechanisms of glomerular damage. Immunological and non-immunological glomerular
lesions
Primitive glomerulonephritis: GN at minimal injury; Acute postinfectious GN; IgA nephropathy; Focal and
segmental glomerulosclerosis; GN membranous; GN membrane-proliferative; GN extracapillary.
Secondary glomerulonephritis: Diabetic nephropathy, lupus nephropathy; vasculitis; cryoglobulinemia;
myeloma nephropathy, amyloidosis.
Interstitial tubular nephropathy, nephrolithiasis and kidney and urinary tract infections: congenital and
acquired renal tubular acidosis, acute and chronic pyelonephritis etc.
Glomerular and tubular hereditary renal diseases (autosomal dominant and recessive polycystic kidney
disease, clinical picture, diagnosis and therapy, Alport disease, Fabry disease etc),
Kidney diseases of vascular origin: Nephrovascular hypertension, benign and malignant
nephroangiosclerosis, atheroembolic disease, renal infarction, renal vein thrombosis.
Books
nefrologia medica C.Ronco edizione piccin
Fisiopatologia renale, l'essenziale, H.G. Renkke, edizione Piccin
Malattie dei reni e delle vie urinarie P.Schena McGraw-Hill Education,
Harrison - Principi di Medicina Interna. Harrison - Fauci - Braunwald - Kasper - Hauser - Longo - Jameson - Loscalzo