THREE-DIMENSIONAL MODELING

Course objectives

Main Objectives The course aims at providing students with theoretical and practical knowledge needed to identify main haematopoietic system diseases and provide evidence-based pharmacological and non-pharmacological therapy. Expected outcomes: competent and critical knowledge of signs, symptoms, diagnostics and therapy of haematopoietic system diseases. Traditional lessons will allow students to properly identify and diagnose main haematopoietic system diseases. Practical lessons will provide students with clinical skills needed to understand signs, symptoms and diagnostics of haematopoietic system diseases. Specific objectives Knowledge and understanding: passing the exam implies the ability of understanding etiopathogenesis, pathophysiology, genetics and clinical aspects of main haematopoietic system diseases. Applying knowledge and understanding: passing the exam implies understanding analytical correlation of clinical signs, symptoms and functional abnormalities with haematopoietic system pathophysiology, risk- and cost effectiveness-based selection of haematopoietic diagnostic work-up, biochemical diagnostic tools and imaging of the haematopoietic system, general concepts of haematopoietic system pathology, related drugs and therapeutic indications according to main European guidelines, non-pharmacological treatment of haematopoietic diseases and main haematopoietic system specific procedures. Making judgment: passing the exam implies the ability of appropriately judging and putting in context medical history, signs and symptoms for appropriate diagnostic work-up and therapy. Communication skills: passing the exam implies mastering the ability to expose clinical reasoning and decision-making from signs and symptoms collection to appropriate diagnosis and therapy. Learning skills: passing the exam implies mastering the ability to learn the rational basis of differential diagnosis.

Channel 1
MARIA ROSARIA RICCIARDI Lecturers' profile

Program - Frequency - Exams

Course program
Clinical approach with the haematologic patient. Blood test in Haematology. Haematopoiesis. Anemias classification. Carential anaemia. Haemolityc anaemia. Marrow failure. Chronic Myeloproliferative diseases. Lymphomas. Chronic Lymphocytic leukaemia. Monoclonal gammopathies. Myelodysplasia. Acute Leukaemias. Physiopathology of Hemostasis. Congenital hemorrhagic diseases. Acquired hemorrhagic diseases. The global care of haematological patients: the role of the haematologist and of the general practicioner. The differences related to gender in haematological diseases. Imaging and Radiotherapy Integrated diagnosis of hemopathies . Interventional radiology in hemorragies and deep tumefaction. Nuclear medicine: erythrocyte survival; lymphoma staging. Therapies.Radiotherapy in haematological malignancies. Laboratory Medicine Laboratory diagnosis of the principal congenital and acquired hemopathies. The role of morphology, immuno phenotype, cytogenetic, and molecular biology as diagnostic tools. Laboratory screening of hemorrhagic diseases. Translational onco-hematology Alterations of cell proliferation and apoptosis. Signal transduction pathways and their aberrant activation in onco-hematology. Alterations in the leukemic cell metabolism. New drugs and molecular therapies targeting the aberrant signaling and the altered metabolism.
Prerequisites
Knowledge of the of haematopoietic system pathophysiology and of biochemistry, cell biology and genetics is essential for a fruitful comprehension of hematopoietic diseases.
Books
Ematologia di Mandelli, a cura di G. Avvisati, 2nd edition, PICCIN 2019 Hematology 2020, ASH Education Program- American Society of Hematology
Teaching mode
The course relies on traditional lessons, interactive teaching and clinical skills education, remote activities and spot light sessions on specific topics, especially for topics subject to relevant updating. Traditional lessons aim at providing theoretical knowledge and are consistent with the aims of the course in terms of knowledge and understanding. Interactive teaching and clinical skills education complete theoretical knowledge by providing in-depth thematic lessons as well as practical clinical skills sessions.
Frequency
The rules relating to the obligation to attend teaching activities are those set out in Article 8 of the course teaching regulations.
Exam mode
The final exam consists of an oral test aimed at evaluating: - knowledge and understanding of the topics covered during the lessons; - use of appropriate scientific terminology and language; - ability to analyze and autonomous reasoning.
Bibliography
Recent bibliography recommended in class.
Lesson mode
The course relies on traditional lessons, interactive teaching and clinical skills education, remote activities and spot light sessions on specific topics, especially for topics subject to relevant updating. Traditional lessons aim at providing theoretical knowledge and are consistent with the aims of the course in terms of knowledge and understanding. Interactive teaching and clinical skills education complete theoretical knowledge by providing in-depth thematic lessons as well as practical clinical skills sessions.
SABRINA MARIANI Lecturers' profile
GIACINTO LA VERDE Lecturers' profile
SABRINA PELLICCIA Lecturers' profile
  • Academic year2025/2026
  • CourseMedicine and Surgery
  • CurriculumSingle curriculum
  • Year4th year
  • Semester1st semester
  • SSDMED/15
  • CFU4