Molecular mechanisms of mitosis

Course objectives

General skills The course is aimed at providing students with an integrated view of the different molecular and cellular components involved in mitosis, highlighting their evolutionary conservation and their role in tumorigenesis and diverse human pathologies; making students familiar with the model systems and the experimental approaches employed to study cell division; providing students with basic notions about the mechanisms of stem cell asymmetric divisions. Specific skills A) Knowledge and understanding - Knowing the main structural and regulatory components of cell division and understanding the molecural interactions controlling its progression. - Knowing the main model systems and experimental approaches to be employed for elucidating specific aspects of mitosis. - Knowing the pathological consequences of alterations in the mitotic process B) Applying knowledge and understanding - To acquire and correctly use the terminology required to describe the main mitotic players and their interactions. - Ability to design suitable experimental approaches for studying specific aspects of cell division. C) Making judgements - To be able to critically evaluate criticamente experimental hypotheses, anche attraverso lo studio e l’approfondimento di esperimenti che hanno portato al chiarimento di particolari aspetti della mitosi. - To be able to correctly interpret the experimental data and to evaluate their statistical significance. D) Communication skills - Ability to perform clear and well-structured oral presentations concerning the course topics, eventually exploiting multimedial supports. E) Learning skills - Acquiring a comprehensive view of the mitotic process and of the high level of evolutionary conservation of its components and regulatory networks. - Learning the suitable terminology to describe components and sub-processes involved in cell division.

Channel 1
MARIA GRAZIA GIANSANTI Lecturers' profile
  • Lesson code1038307
  • Academic year2025/2026
  • CourseCell biology and technology
  • CurriculumSingle curriculum
  • Year1st year
  • Semester2nd semester
  • SSDBIO/18
  • CFU6