Catalogo dei Corsi di studio

Prof. Ottini s expertise is in the area of genetics and molecular epidemiology of human solid tumors, with specific interest in breast, prostate and gastrointestinal cancer.
In these fields, she has authored more than 150 peer-reviewed publications.
Prof.Ottini currently is
- Head of the Molecular Epidemiology Research Unit, Department of Molecular Medicine Sapienza University of Rome
- Coordinator of the Italian Multicentre Study on Male Breast Cancer
- PI of the male breast cancer research study within the Consortium of Investigators of Modifiers of BRCA1/2 (CIMBA)
- Co-leader of the International Consortium on Male Breast Cancer Genetics (MERGE)
She has specific expertise in:
- Genomic screening of cancer patients by NGS (Next generation sequencing) for the identification of cancer susceptibility genes.
- Investigation of common genetic variants in the susceptibility of tumors by GWAS (Genome Wide Association Studies).
- Identification of genetic modifiers of neoplastic risk in mutation carriers by population-based case-control studies.
- Tumor profiling for the characterization of genetic and epigenetic signatures by genome, transcriptome and DNA methyloma analysis.
- Development of Polygenic Risk Score (PRS) models for accurate cancer risk prediction.