GABRIELLA DOBROWOLNY

Personal Data:
Address: Dept. of Histology and Medical Embriology. Medical School University of Rome.
e-mail gabriella.dobrowolny@uniroma1.it

Education:
1998 Degree cum laude in Biology, University of Rome “La Sapienza”.
1998-1999 Specialized School degree in “Analytical references and Quality Control” at the University of Rome “La Sapienza”.
2004 PhD in Cell Science and Morphogenesis. Thesis title: “Enhanced expression of IGF1 attenuates muscle wasting in aging and Amyotrophic Lateral Sclerosis”.
2014 Specialist in Clinical Pathology
Training and working experience
1998-1999 “Research Fellow” at the Istituto Superiore di Sanità of Rome in Laboratory of Comparative Toxicology and Ecotoxicology.
1999-2003 PhD student at the Dept. of Histology and Medical Embryology, Medical school university of Rome, Italy
2003-2008 “Post-doctoral Fellow” at Dept. of Histology and Medical Embryology, Medical School University of Rome, focusing her study on muscle dystrophy, neuromuscular disease, and on the profund consequences of oxidative stress on skeletal muscle tissue.
2003 “Academic Visitor” in the Biomic Center of the St. George Hospital Medical School London. During this period she improved her technical skills in the biochemical fields, learning to use the SELDI -TOF and MALDI –TOF Mass Spectrometer.
2006 “Honorary research fellow” in the Biomic Center of the St. George University of London. During this period she performed a proteomic study on the interplay between skeletal muscle and nervous tissue.
2006-2007 Research fellow for Association Française contre les Myopathies (AFM) on the study of the molecular mechanism of the interplay between muscle and nerve in a mouse model of ALS disease
2007-2013 Post Doc Fellow at DAHFMO - Unit of Histology and Medical Embryology Sapienza University of Rome.

2013-2018 Research Fellow at IIT – CNLS for the project NATURA (Nanotech Approaches for The stUdy and cuRe of Als)

2019-2025 Researcher at at DAHFMO - Unit of Histology and Medical Embryology Sapienza University of Rome.
2025-today Associate Professor at DAHFMO - Unit of Histology and Medical Embryology Sapienza University of Rome.

Teaching activity

2020/21-present lecturer in Histology and Medical Embryology - Medicine and Surgery school degree CdL HT -CdL B- CdL C -Sapienza University-Rome
2019/2020-present lecturer in Histology- Fisioterapy school degree- CdL C Ospedale. San Giovanni-Addolorata Sapienza University –-Rome
2019/2020-present lecturer in Histology Nursery school degree - CdL G ASL RM 5 Colleferro (RM) and CdL E Ospedale S. Spirito Sapienza University - Rome
2019/2020-present lecturer in Histology–Medical radiology imaging techniques and radiotherapy school degree–CdL A Policlinico Umberto I Sapienza University -Rome
2019/2020-present lecturer in Genetics–Medical radiology imaging techniques and radiotherapy school degree–CdL A Policlinico Umberto Sapienza University - Rome
2015/16 lecturer in Histology Nursery school degree –CdL H ASL RM 6 Nettuno (RM) Sapienza University -Rome
2008/09 -2011/2012 lecturer in Histology Nursery school degree-CdL B Policlinico Umberto I Sapienza University -Rome

Scientific activity

Studies of the metabolic profile and muscle-nerve communication in physiological and pathological condition such as in ALS disease. Through the professional experience in the biomedical field as research scientist and clinical pathology specialist she has developed deep knowledge in the fields of skeletal muscle and nervous tissue communication in ALS disease pathogenesis. The scientific work lead to the publication of 45 papers, six of which has been published in high scientific impact journal such as Nat. Gen. (2001), PNAS (2004), JCB (2005) Cell Metab. (2008), ARS (2018), Sci. Rep. (2019), Br J Pharmacol. (2022), J Cachexia Sarcopenia Muscle. (2025)
Editorial activity: Member of the Editorial Board of “Scientific Report”-Springer Nature 2024;-Member of the Editorial Board of Stem Cell Research as Review Editor for Frontiers in Cell and Developmental Biology, Frontiers in Genetics, Frontiers in Oncology and Frontiers in Bioengineering and Biotechnology 2024;-Guest Editor for Cells in the special issue The Role of Skeletal Muscle in Neuromuscular Diseases: From Cellular and Molecular Players to Therapeutic Interventions-2021; -Guest Editor for the International Journal of Molecular Sciences in the special issue “Skeletal Muscle Wasting, Regeneration, and Stem Cells”,
-Referee activity for PLOS ONE, Experimental Gerontology Scientific Reports international journals and for the Research Fund - Flanders (FWO) - Fund for Scientific Research