Notizie
AVVISO
Ricevimento: su appuntamento
Orari di ricevimento
su appuntamento
Curriculum
PERSONAL INFORMATION
Family name: Ventura
First name: Rossella
ORCID:https://orcid.org/0000-0002-7601-8683; Scopus Author ID:7102796694; Research ID:AAA-8816-2019
Nationality: Italy
EDUCATION AND TRAINING
-1995. Degree in Experimental Psychology, “Sapienza” University of Rome.
-1996-1997. Scholarship at the Department of Psychology, “Sapienza” University of Rome.
-1998. Scholarship at the Laboratory of Molecular Genetics, Institute OASI MSS, IRCCS, Troina, Italy.
-1997-2000. Ph.D in Psychobiology and Psychopharmacology, Department of Psychology, University of Rome “Sapienza”.
-2000-2001. Postdoctoral fellowship at the Department of Psychology “Sapienza” University (fellowship title: “Role of the mesocorticolimbic and cerebellar system in learning and memory”).
-2001-2005. Associate Researcher at the Department of Psychology, “Sapienza” University of Rome.
- 2002: Recipient of a grant by the Research Committee of the University of Rome (Project Title: Role of dopaminergic and noradrenergic transmission in cognitive and behavioral deficits in a genetic mouse model of Fragile- X”).
- 2005-2022. Researcher Fondazione Santa Lucia, IRCCS, (European Centre for Brain Research, CERC), Rome.
Since 2023. RCCS San Raffaele, Rome
CURRENT POSITION
Since 2012 Associate Prof, Dep of Psychology, Sapienza University Rome Italy
PREVIOUS POSITIONS
2005-2007 Researcher Dep of Science of Education, L’Aquila University, Italy
2007-2012 Researcher Dep of Psychology, L’Aquila University, Italy
FELLOWSHIPS AND AWARDS
2000-2005 Postdoctoral fellowship, Psychology Dep, Sapienza Univ, Rome Italy
2001 Licensed Psychology
Since 2000 Aggregate Researcher Neurobiology of Behavior lab; Santa Lucia Found IRCCS Rome, Italy
2002 Winner of the grant "Young Res" Dep of Psychology, Sapienza Univ Rome, Italy
2015 (tornata 2013) and 2020 (tornata 2018) Qualification to the full professor rank (Abilitazione Scientifica Nazionale I fascia) M-PSI/02.
Since 2024 (sept) member of “UNESCO Chair Child maltreatment”
ORAL PRESENTATION (INVITED)
2014 FENS
2014 1st International Congress on Chocolate and Cocoa in Medicine
2017 SINS
2023 Development Neuropsychology 18-22 January (Brixen)
2023 UNESCO Chair on Children Maltreatment 19 June (Rome)
FUNDINGS (Principal Investigator)
2002 Young Res Sapienza Univ Rome, Italy 6.500
2012-2017 FIRB 2010-RBFR10RZ0N Ministry of Instruction Univ and Research, Italy 493.960
2013 C26A13L3PZ Sapienza Univ Rome Italy 7.000
2015 C26A15S53E Sapienza Univ Rome Italy 8.000
2016 C351BDB6 Sapienza Univ Rome Italy 31.600
2017 RG11715C7E0A7187 Sapienza Univ Rome Italy 34.500
2018 RP118164336EF3FD Sapienza Univ Rome Italy 3.000
2020 Zardi-Gori Post-doctoral Fellowships 27.000
2020 RM120172B7A3A801 Sapienza Univ Rome Italy 10.000
2021 RG12117A5C2F8800 Sapienza Univ Rome Italy 68.787
2023 RP123188ED6560C7 Sapienza Univ Rome Italy € 3.000
2024 2022FWME9W (PRIN 2022) Ministero della Ricerca Italy € 177.857
2024 RG124190FD838AAC Sapienza Univ Rome Italy € 30.380,00
LABORATORY TEAM LEADER: SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS
Since 2012 Team leader of Psychobiology Lab (Dep Psychology, Sapienza Univ, Rome Italy).
My main interest has always been the psychobiology of mental diseases with a special focus on the role of genetic, environmental and epigenetic factors interaction in their development, as documented by peer-reviewed publications. My training as a cognitive-behavioral therapist helped me to develop animal models capable of connecting neurobiological phenotypes with psycho-pathogenic pathways.
I have expertise, leadership, training, and motivation necessary to successfully carry out the proposed research.
I have a broad background in preclinical research specific expertise in animal models of psychopathologies. As documented by peer-reviewed publications, my research includes neurochemical, behavioral and molecular changes associated with psychopathologies induced by stress exposure on preclinical models, and I master many in vivo methods for in-vivo experimentation in mice.
TEACHING ACTIVITIES
Since 2005 at least 120 hours of teaching per year (M-PSI/02), Dep of Science of Education and Dep Psychology Univ of L’Aquila; Dep Psychology, Sapienza Univ, Rome Italy.
INSTITUTIONAL RESPONSIBILITIES
2006-2012 Member of the PhD program in Neurobiology of neurodegenerative disease, plasticity and neural development, Univ of L’Aquila, Italy
Since 2013 Team Leader Psychobiology Lab, Dep Psychology, Sapienza Univ, Rome Italy
Since 2013 Member of the PhD program in Behavioral Neuroscience, Dep Psychology, Sapienza Univ, Rome Italy
Since 2014 Member of the Board “evaluation of foreign titles”, Dep. Psychology, Sapienza Univ, Rome Italy
Since 2018 Member of the Board “PTI”, Dep Psychology, Sapienza Univ, Rome Italy
Since 2021 (Ott) Member of the Department Board, Dep. Psychology, Sapienza Univ, Rome Italy
Since 2022 (14 December) Member of the Faculty Board, Sapienza Univ, Rome Italy
Since 2024 Member of Quality Team (Laurea Magistrale in Neuroscienze Cognitive e
Riabilitazione Psicologica), Dep. Psychology, Sapienza Univ, Rome Italy
Since 2024 (October) Membro dell’Osservatorio della Didattica, Magistrale Neuroscience Cognitive e riabilitazione psicologica, Dipartimento di Psicologia, Sapienza
REVIEWING ACTIVITIES
Funding organizations
Grant review: ANR, MIUR (France and Italian Ministry for Scientific Research, respectively).
United States-Israel Binational Science Foundation.
Review for peer-reviewed international journals: Cer Cortex, PloSOne; Behav Brain Res, Add Biol, Neuropharm, Neurosci, Scientific Rep…
2021. Topic Editor for Research Topic "Long-Term Effects of Early-Life Manipulations: Risks and Advantages for Neurodevelopment” for Frontiers In Cellular Neuroscience published 07/06/2021.
2022. Topic Editor for Research Topic “Dysfunctional Motivation in Eating Behaviors: A Complex Gene x Environment Interplay “ for Frontiers in Behavioral Neuroscience published 31/05/2022.
Editorial activity
Since May 2023.Associate Editor for Cellular Neurophysiology (section of Frontiers in Cellular Neuroscience).
MEMBERSHIPS OF SCIENTIFIC SOCIETIES
Member of “Society for Neuroscience”, EBPS (European Behavioural Pharmacology Society).
Italian Stress Network
Publications
1. Cabib S, Oliverio A, Ventura R, Lucchese F, Puglisi-Allegra S (1997). Brain dopamine receptor plasticity: testing a diathesis-stress hypothesis in an animal model. Psychopharmacology, 132 (2): 153-160. Indice Scopus 2-s2.0-0030743304. ISSN: 00333158; DOI: 10.1007/s002130050331. (IF 2.933)
2. D'Amato FR, Cabib S, Ventura R, Orsini C (1998). Long term effects of post-natal manipulation on emotionality are prevented by maternal anxiolytic treatment in mice. Developmental Psychobiology, 32(3): 225-234. Indice Scopus 2-s2.0-0031657177. ISSN: 00121630; DOI: 10.1002/(sici)1098-2302(199804)32:3<225::aid-dev6>3.0.co;2-q. (IF 1.435)
3. Castellano C, Ventura R, Cabib S, Puglisi-Allegra S (1999). Strain-dependent effects of anandamide on memory consolidation in mice are antagonized by naltrexone. Behavioural Pharmacology, 10(5): 453-457. Indice Scopus 2-s2.0-0032845754. ISSN: 09558810; DOI: 10.1097/00008877-199909000-00003. (IF 1.852)
4. Persico AM, Altamura C, Calia E, Puglisi-Allegra S, Ventura R, Lucchese F, Keller F (2000). Serotonin depletion and barrel cortex development: impact of growth impairment vs serotonin effects on thalamocortical endings. Cerebral Cortex, 10(2): 181-191. Indice Scopus 2-s2.0-0033960979. ISSN: 10473211; PubMed ID: doi: 10.1093/cercor/10.2.181 (IF 4.822)
5. Puglisi-Allegra S, Cabib S, Pascucci T, Ventura R, Calì F, Romano V (2000) Dramatic brain aminergic deficits in a genetic mouse model of phenylketonuria. NeuroReport, 11 (6), 1361-1365. Indice Scopus 2-s2.0-0034720267. ISSN: 09594965; DOI: 10.1097/00001756-200004270-00042. (IF 2.696)
6. Ventura R, Cabib S, Puglisi-Allegra S. (2001). Opposite genotype-dependent mesocorticolimbic dopamine response to stress. Neuroscience. 104(3): 627-31. Indice Scopus 2-s2.0-0035859188. ISSN: 03064522; DOI: 10.1016/S0306-4522(01)00160-9. (IF 3.219)
7. Cabib S, Ventura R, Puglisi-Allegra S (2002). Opposite imbalances between mesocortical and mesoaccumbens dopamine responses to stress by the same genotype depending on living conditions. Behavioural Brain Research, 129(1-2): 179-185. Indice Scopus 2-s2.0-0036467169. ISSN: 01664328; DOI: 10.1016/S0166-4328(01)00339-4. (IF 2.791)
8. Cabib S, Puglisi-Allegra S, Ventura R (2002). The contribution of comparative studies in inbred strains of mice to the understanding of the hyperactive phenotype. Behavioural Brain Research, 130(1-2):103-109. Indice Scopus 2-s2.0-0037051134. ISSN: 01664328; DOI: 10.1016/S0166-4328(01)00422-3. (IF 2.791)
9. Orsini C, Ventura R, Lucchese F, Puglisi-Allegra S, Cabib S (2002). Predictable stress promotes place preference and low mesoaccumbens dopamine response. Physiology and Behavior, 75(1-2): 135-141. Indice Scopus 2-s2.0-0036466040. ISSN: 00319384; DOI: 10.1016/S0031-9384(01)00629-1. (IF 1.652)
10. Ventura R, Cabib S, Puglisi-Allegra S (2002). Genetic susceptibility of mesocortical dopamine to stress determines liability to inhibition of mesoaccumbens dopamine and to behavioral ‘despair’ in a mouse model of depression. Neuroscience, 115 (4): 999-1007. Indice Scopus 2-s2.0-0037121629. ISSN: 03064522; DOI: 10.1016/S0306-4522(02)00581-X. (IF 3.457)
11. Alcaro A, Cabib S, Ventura R, Puglisi-Allegra S (2002). Genotype- and experience-dependent susceptibility to depressive-like responses in the forced-swimming test. Psychopharmacology, 164 (2): 138-143. Indice Scopus 2-s2.0-0036914013. ISSN: 00333158; DOI: 10.1007/s00213-002-1161-8. (IF 3.275)
12. Pascucci T, Ventura R, Puglisi-Allegra S, Cabib S (2002). Deficits in brain serotonin synthesis in a genetic mouse model of phenylketonuria. NeuroReport, 13(18): 2561-2564. Indice Scopus 2-s2.0-0037147660. ISSN: 09594965; DOI: 10.1097/00001756-200212200-00036. (IF 2.265)
13. Ventura R, Cabib S, Alcaro A, Orsini C, Puglisi-Allegra S (2003). Norepinephrine in the prefrontal cortex is critical for amphetamine-induced reward and mesoaccumbens dopamine release. The Journal of Neuroscience, 23(5): 1879-1885. Indice Scopus 2-s2.0-0037335748. ISSN: 02706474; doi: 10.1523/JNEUROSCI.23-05-01879.2003 PubMed ID: 12629192. (IF 8.306)
14. Cabib S, Pascucci T, Ventura R, Romano V, Puglisi-Allegra S (2003). The behavioral profile of severe mental retardation in a genetic mouse model of phenylketonuria. Behavior Genetics, 33 (3): 301-310. Indice Scopus 2-s2.0-0038439345. ISSN: 00018244; DOI: 10.1023/A:1023498508987. (IF 3.03)
15. Ventura R, Alcaro A, Cabib S, Conversi D, Mandolesi L, Puglisi-Allegra S (2004). Dopamine in the medial prefrontal cortex controls genotype-dependent effects of amphetamine on mesoaccumbens dopamine release and locomotion. Neuropsychopharmacology, 29 (1): 72-80. Indice Scopus 2-s2.0-0346057790. ISSN: 0893133X; DOI: 10.1038/sj.npp.1300300. (IF 4.941)
16. Ventura R, Alcaro A, Mandolesi L, Puglisi-Allegra S (2004). In vivo evidence that genetic background controls impulse-dependent dopamine release induced by amphetamine in the nucleus accumbens. Journal of Neurochemistry, 89: 494-502. Indice Scopus 2-s2.0-1942423562. ISSN: 00223042; DOI: 10.1111/j.1471-4159.2004.02342.x. (IF 4.824)
17. Ventura R, Pascucci T, Catania MT, Musumeci SA, Puglisi-Allegra S (2004). Object recognition impairment in FMR1 knockout mice is reversed by amphetamine: involvement of dopamine in the medial prefrontal cortex. Behavioural Pharmacology, 15: 433-442. Indice Scopus 2-s2.0-4544383988. ISSN: 09558810; DOI: 10.1097/00008877-200409000-00018. (IF 2.301)
18. Ventura R, Alcaro A, Puglisi-Allegra S (2005). Prefrontal cortical norepinephrine release is critical for morphine-induced reward, reinstatement and dopamine release in the nucleus accumbens. Cerebral Cortex. 15: 1877-214. Indice Scopus 2-s2.0-23344452414. ISSN: 10473211; DOI: 10.1093/cercor/bhi066. (IF 6.187)
19. Ventura R, Puglisi-Allegra S. (2005). Environment makes amphetamine-induced dopamine release in the nucleus accumbens totally impulse-dependent. Synapse. 58(3):211-214. Indice Scopus 2-s2.0-26644449806. ISSN: 08874476; DOI: 10.1002/syn.20197. (IF 3.220)
20. Schank JR*, Ventura R*, Puglisi-Allegra S, Alcaro A, Cole CD, Liles LC, Seeman P, Weinshenker D. (2006). Dopamine beta-Hydroxylase Knockout Mice have Alterations in Dopamine Signaling and are Hypersensitive to Cocaine. Neuropsychopharmacology. 31 (10): 2221-2230. Indice Scopus 2-s2.0-33748770069. ISSN: 0893133X; DOI: 10.1038/sj.npp.1301000. (IF 5.889) * co-first author
21. Ventura R, De Carolis D, Alcaro A, Puglisi-Allegra S (2006). Ethanol consumption and reward depend on norepinephrine in the prefrontal cortex. Neuroreport. 17(17):1813-1817. Indice Scopus 2-s2.0-33845675403. ISSN: 09594965; DOI: 10.1097/01.wnr.0000239964.83566.75. (IF 2.137)
22. Ventura R, Morrone C, Puglisi-Allegra S (2007). Prefrontal/accumbal cathecolamine system determines motivational salience attribution to both reward- and aversion-relate stimuli. Proct Natl Acad Sci USA. 104 (12): 5181-5186. Indice Scopus 2-s2.0-34247616741. ISSN: 00278424; DOI: 10.1073/pnas.0610178104. (IF 9.598)
23. Pascucci T, Ventura R, Latagliata C, Cabib S, Puglisi-Allegra S (2007). The Medial Prefrontal Cortex Determines the Accumbens Dopamine Response to Stress through the Opposing Influences of Norepinephrine and Dopamine. Cerebral Cortex. 17(12):2796-804. Indice Scopus 2-s2.0-36248987227. ISSN: 10473211; DOI: 10.1093/cercor/bhm008. (IF 6.519)
24. Ventura R, Latagliata E.C., Morrone C., La Mela I., Puglisi-Allegra, S. (2008). Prefrontal Norepinephrine Determines Attribution of ‘‘High’’ Motivational Salience. PLoS ONE 3 (8) e3044. Indice Scopus 2-s2.0-52449098276. ISSN: 19326203; DOI: 10.1371/journal.pone.0003044. (IF 4.35)
25. Pascucci T, Andolina D, Ventura R, Puglisi-Allegra S, Cabib S. (2008). Reduced availability of brain amines during critical phases of postnatal development in a genetic mouse model of cognitive delay. Brain Res. 1217: 232-238. Indice Scopus 2-s2.0-45449105540. ISSN: 00068993; DOI: 10.1016/j.brainres.2008.04.006. (IF 2.494)
26. Pascucci T, Andolina D, Mela IL, Conversi D, Latagliata C, Ventura R, Puglisi-Allegra S, Cabib S (2009). 5-Hydroxytryptophan rescues serotonin response to stress in prefrontal cortex of hyperphenylalaninaemic mice. Int J Neuropsychopharmacol. 12(8):1067-79. Indice Scopus 2-s2.0-69749104924. ISSN: 14611457; DOI: 10.1017/S1461145709990381. (IF 4.378)
27. La Mela I, Latagliata EC, Patrono E, Puglisi-Allegra S, Ventura R (2010). Olfactory priming reinstates extinguished chocolate-induced conditioned place preference. Appetite Feb;54(1):237-40. Indice Scopus 2-s2.0-74449083809. ISSN: 01956663; DOI: 10.1016/j.appet.2009.12.008. (IF 2008 2.341)
28. Latagliata EC, Patrono E, Puglisi-Allegra S, Ventura R (2010). Food seeking in spite of harmful consequences is under prefrontal cortical noradrenergic control. BMC Neuroscience Feb 8;11:15. Indice Scopus 2-s2.0-77249169869. ISSN: 14712202; DOI: 10.1186/1471-2202-11-15. (IF 2008 2.85)
29. Andolina D, Conversi D, Cabib S, Trabalza A, Ventura R, Puglisi-Allegra S, Pascucci T (2011). 5-Hydroxytryptophan during critical postnatal period improves cognitive performances and promotes dendritic spine maturation in genetic mouse model of phenylketonuria. Int J Neuropsychopharmacol. 14(4):479-89. Indice Scopus 2-s2.0-79960344958. ISSN: 14611457; DOI: 10.1017/S1461145710001288. (IF 4.578)
30. D'Amato FR, Zanettini C, Lampis V, Coccurello R, Pascucci T, Ventura R, Puglisi-Allegra S, Spatola CA, Pesenti-Gritti P, Oddi D, Moles A, Battaglia M (2011). Unstable maternal environment, separation anxiety, and heightened CO2 sensitivity induced by gene-by-environment interplay. PLoS One. 8;6(4):e18637. Indice Scopus 2-s2.0-79954467877. ISSN: 19326203; DOI: 10.1371/journal.pone.0018637. (IF 4.35)
31. Puglisi-Allegra S, Ventura R (2012). Prefrontal/accumbal catecholamine system processes high motivational salience. Front Behav Neurosci. 6:31. Epub Jun Indice Scopus 2-s2.0-84864386102. ISSN: 16625153; DOI: 10.3389/fnbeh.2012.00031. (IF 4.8)
32. Puglisi-Allegra S, Ventura R (2012). Prefrontal/accumbal catecholamine system processes emotionally driven attribution of motivational salience. Reviews in the Neuroscience 23 (5-6) , pp. 509-526. Indice Scopus 2-s2.0-84869444987. ISSN: 03341763; DOI: 10.1515/revneuro-2012-0076. (IF 2.6)
33. Ventura R, Coccurello R, Andolina D, La tagliata E C, Zanettini C, Lampis V, Battaglia M D’Amato FR, Moles A. (2013). Postnatal Aversive Experience Impairs Sensitivity to Natural Rewards and Increases Susceptibility to Negative Events in Adult Life. Cerebral Cortex 23 (7) , pp. 1606-1617. Indice Scopus 2-s2.0-84878820780. ISSN: 10473211; DOI: 10.1093/cercor/bhs145. (IF 6.828)
34. Pascucci T, Giacovazzo G, Andolina D, Accoto A, Fiori E, Ventura R, Orsini C, Conversi D, Carducci C, Leuzzi V, Puglisi-Allegra S (2013). Behavioral and neurochemical characterization of new mouse model of hyperphenylalaninemia. PLoS One. 20;8(12):e84697. Indice Scopus: 2-s2.0-84893189946; ISSN: 19326203; DOI: 10.1371/journal.pone.0084697. (IF 3.73).
35. Di Segni M, Patrono E, Patella L, Puglisi-Allegra S, Ventura R (2014). Animal models of compulsive eating behavior. Nutrients. Oct 22;6(10):4591-609. Indice Scopus: 2-s2.0-84908199189. ISSN: 20726643; DOI: 10.3390/nu6104591. (IF 3.27)
36. Duarte RB, Patrono E, Borges AC, César AA, Tomaz C, Ventura R, Gasbarri A, Puglisi-Allegra S, Barros M. (2014). Consumption of a highly palatable food induces a lasting place-conditioning memory in marmoset monkeys. Behav Processes. Sep;107:163-1666. Indice Scopus: 2-s2.0-84908086796. ISSN: 03766357; DOI: 10.1016/j.beproc.2014.08.021. (IF 1.567)
37. Duarte RBM, Patrono E, Borges AC, Tomaz C, Ventura R, Gasbarri A, Puglisi-Allegra S, Barros M (2015). High versus low fat/sugar food affects the behavioral, but not the cortisol response of marmoset monkeys in a conditioned-place-preference task. Physiology and Behavior, 139: 442-448. Indice Scopus: 2-s2.0-84919363652. ISSN: 00319384; DOI: 10.1016/j.physbeh.2014.11.065. (IF 2.461)
38. Andolina D, Puglisi-Allegra S, Ventura R (2015). Strain-dependent differences in corticolimbic processing of aversive or rewarding stimuli. Frontiers in Systems Neuroscience, Vol 8, Article number 207, 6p. Indice Scopus: 2-s2.0-84923254774. ISSN: 16625137; DOI: 10.3389/fnsys.2014.00207
39. Patrono E, Di Segni MD, Patella L, Andolina D, Valzania A, Latagliata EC, Felsani A, Pompili A, Gasbarri A, Puglisi-Allegra S, Ventura R (2015). When chocolate seeking becomes compulsion: Gene-environment interplay. PLoS ONE vol 10, Issue 3, e0120191. Indice Scopus: 2-s2.0-84924975766. ISSN: 19326203; DOI: 10.1371/journal.pone.0120191. (IF 3.057)
40. Fiori E, Babicola L, Andolina D, Coassin A, Pascucci T, Patella L, Han YC, Ventura A, Ventura R (2015). Neurobehavioral Alterations in a Genetic Murine Model of Feingold Syndrome 2. Behav Genet. 2015 Sep;45(5):547-59. Indice Scopus: 2-s2.0-84941187375. ISSN: 00018244; DOI: 10.1007/s10519-015-9724-8. (IF 3.268)
41. Di Segni M, Andolina D, Luchetti A, Babicola L, D’Apolito LI, Pascucci T, Conversi D, Accoto A, D’Amato FR, Ventura R (2016). Unstable maternal environment affects stress response in adult mice in a genotype-dependent manner. Cerebral Cortex 26(11):4370-4380. Indice Scopus: 2-s2.0-84994627631. ISSN: 10473211; DOI: 10.1093/cercor/bhv204. (IF 6.559)
42. Andolina D, Di Segni M, Bisicchia E, D'Alessandro F, Cestari V, Ventura A, Concepcion C, Puglisi-Allegra S, Ventura R. (2016). Effects of lack of microRNA-34 on the neural circuitry underlying the stress response and anxiety. Neuropharmacology. 2016 Aug;107:305-316. Indice Scopus: 2-s2.0-84962719902. ISSN: 00283908; DOI:10.1016/j.neuropharm.2016.03.044. (IF 5.012)
43. Andolina D, Di Segni M, Ventura R (Online 2016; 2017). MiRNA-34 and stress response. Oncotarget. Published online 2016; 2017 Jan 24;8(4):5658-5659. Indice Scopus: 2-s2.0-85010766644. ISSN: 19492553; DOI: 10.18632/oncotarget.13923. (IF 5.168)
44. Fiori E, Oddi D, Ventura R, Colamartino M, Valzania A, D'Amato FR, Bruinenberg V, van der Zee E, Puglisi-Allegra S, Pascucci T. (2017). Early-onset behavioral and neurochemical deficits in the genetic mouse model of phenylketonuria. PLoS One. 2017 Aug 29;12(8):e0183430. Indice Scopus: 2-s2.0-85029153794. ISSN: 19326203.; DOI: 10.1371/journal.pone.0183430. (IF 2.766)
45. Di Segni M, Andolina D, Coassin A, Accoto A, Luchetti A, Pascucci T, Luzi C, Lizzi AR, D'Amato FR, Ventura R (2017). Sensitivity to cocaine in adult mice is due to interplay between genetic makeup, early environment and later experience. Neuropharmacology. 2017 Oct;125:87-98. Indice Scopus: 2-s2.0-85025170709. ISSN: 00283908; DOI: 10.1016/j.neuropharm.2017.07.014. (IF 4.249)
46. Di Segni M, Andolina D, Ventura R* (2018). Long-term effects of early environment on the brain: Lesson from rodent models. Seminars in Cell & Developmental Biology. Oct 7. pii: S1084-9521(17)30288-4. Indice Scopus: 2-s2.0-85030626672. ISSN: 10849521; DOI: 10.1016/j.semcdb.2017.09.039. (IF 5.460)
47. Latagliata EC, Puglisi-Allegra S, Ventura R, Cabib S (2018). Norepinephrine in the medial pre-frontal cortex supports accumbens shell responses to a novel palatable food in food-restricted mice only. Frontiers In Behavioral Neuroscience, vol. 12,7. Indice Scopus: 2-s2.0-85041283008. ISSN: 1662-5153, DOI: 10.3389/fnbeh.2018.00007. (IF 2.622)
48. Andolina D, Di Segni M, Accoto A, Lo Iacono L, Borreca A, Ielpo D, Berretta N, Perlas E, Puglisi-Allegra S, Ventura R (2018). MicroRNA-34 Contributes to the Stress-related Behavior and Affects 5-HT Prefrontal/GABA Amygdalar System through Regulation of Corticotropin-releasing Factor Receptor 1. Molecular Neurobiology, Indice Scopus: 2-s2.0-85041507704. ISSN: 08937648. DOI: 10.1007/s12035-018-0925-z. (IF 4.586)
49. Lacal I, Ventura R (2018). Epigenetic inheritance: concepts, Mechanisms and Perspectives. Frontiers in Molecular Neuroscience, 11,292. Indice Scopus: 2-s2.0-85054854101. ISSN: 16625099; DOI: 10.3389/fnmol.2018.00292. (IF 3.720)
50. Pascucci, T, Rossi L, Colamartino M, Gabucci C, Carducci C, Valzania A, Sasso V, Bigini N, Pierigè F, Viscomi MT, Ventura R, Cabib S, Magnani M, Puglisi-Allegra S, Leuzzi V (2018). A new therapy prevents intellectual disability in mouse with phenylketonuria. Molecular Genetics and Metabolism, 124: 39-49. Indice Scopus: 2-s2.0-85045301430. ISSN: 10967192; DOI: 10.1016/j.ymgme.2018.03.009. (IF 3.610)
51. Di Segni M, Andolina D, D'Addario SL, Babicola L, Ielpo D, Luchetti A, Pascucci T, Lo Iacono L, D'Amato FR, Ventura R (2019). Sex-dependent effects of early unstable postnatal environment on response to positive and negative stimuli in adult mice. Neuroscience, 413:1-10. Indice Scopus: 2-s2.0-85067853998 ISSN: 03064522; DOI: 10.1016/j.neuroscience.2019.06.016. (IF 3.056)
52. Lo Iacono L, Ielpo D, Accoto A, Di Segni M, Babicola L, D’Addario SL, Ferlazzo F, Pascucci T, Ventura R*, Andolina D (2020) Corresponding author. MicroRNA-34a regulates the depression-like behavior in mice by modulating the expression of target genes in the Dorsal Raphè. Molecular Neurobiology 57 (2): 823 – 836. Indice Scopus 2-s2.0-85071772292, ISSN: 08937648; DOI: 10.1007/s12035-019-01750-2. (IF 5.590)
53. Di Segni M, D’Addario SL, Babicola L, Ielpo D, Lo Iacono L, Andolina D, Accoto A, Luchetti A, Mancini C, Parisi C, D’Onofrio M, Arisi I, Brandi R, Pascucci T, Cifani C, D’Amato FR, Ventura R (2020). Xlr4 as a new candidate gene underlying vulnerability to cocaine effects. Neuropharmacology, May 15;168:108019. Indice Scopus 2-s2.0-85081004285; ISSN 00283908; PMID: 32113966; DOI: 10.1016/j.neuropharm.2020.108019. (IF 5.250)
54. Babicola L, Pietrosanto M, Ielpo D, D’Addario SL, Cabib S, Ventura R, Ferlazzo F, Helmer-Citterich M, Andolina D, Lo Iacono L (2020). RISC RNA sequencing in the Dorsal Raphè reveals microRNAs regulatory activities associated with behavioral and functional adaptations to chronic stress. Brain Research 1736. Indice Scopus 2-s2.0-85081672685, ISSN 00068993 DOI: 10.1016/j.brainres.2020.146763. (IF 3.252)
55. Pascucci T, Colamartino T, Fiori E, Sacco R, Coviello A, Ventura R, Puglisi-Allegra S, Turriziani L, Persico AM (2020). P-cresol alters brain dopamine metabolism and exacerbates autism-like behaviors in the BTBR mouse. Brain Sciences, vol. 10, Indice Scopus 2-s2.0-85083801548, ISSN: 2076-3425, DOI: 10.3390/brainsci10040233. (IF 3.394)
56. Babicola L, Ventura R*, D’Addario SL, Ielpo D, Andolina R, Di Segni M (2021). Long term effects of early life stress on HPA circuit in rodent models. Molecular and Cellular Endocrinology. Available online 15 December 2021. Indice Scopus 2-s2.0-85098095336, ISSN 03037207; PMID: 33333214. DOI 10.1016/j.mce.2020.111125; (IF 4.102) Corresponding author
57. Lo Iacono L, Ielpo D, Parisi C, Napoli G, Accoto A, Di Segni M, Babicola L, D'Addario SL, Guzzo SM, Pascucci T, Ventura R, Andolina D (2021). MicroRNA-34a regulates 5-HT2C expression in Dorsal Raphe and contributes to the anti-depressant-like effect of fluoxetine. Neuropharmacology. Apr 9:108559. Indice Scopus 2-s2.0-85104079200, ISSN 00283908; PMID: 33845072. DOI: 10.1016/j.neuropharm.2021.108559. (IF 5.250)
58. Rossi L, Nardecchia F, Pierigè F, Ventura R, Carducci C, Leuzzi V, Magnani M, Cabib S, Pascucci T (2021). Intellectual Disability and Brain Creatine Deficit: Phenotyping of the Genetic Mouse Model for GAMT Deficiency. Genes (Basel) Aug 2;12(8):1201. Indice Scopus 2-s2.0-85112630611, ISSN 20734425; PMID: 34440375; PMCID: PMC8391262. DOI: 10.3390/genes12081201. (IF 4.096)
59. D'Addario SL, Di Segni M, Ledonne A, Piscitelli R, Babicola L, Martini A, Spoleti E, Mancini C, Ielpo D, D'Amato FR, Andolina D, Ragozzino D, Mercuri NB, Cifani C, Renzi M, Guatteo E, Ventura R (2021). Resilience to anhedonia-passive coping induced by early life experience is linked to a long-lasting reduction of Ih current in VTA dopaminergic neurons. Neurobiology of Stress. Apr 15;14:100324. Indice Scopus 2-s2.0-85104148559, ISSN 23522895; PMID: 33937445; PMCID: PMC8079665. DOI: 10.1016/j.ynstr.2021.100324. (IF 5.441)
60. Luchetti A, Di Segni M, Andolina D, Ventura R, Battaglia M, D'Amato FR (2021). Mouse model of panic disorder: Vulnerability to early environmental instability is strain-dependent. Dev Psychobiol. Sep;63(6):e22135. doi: 10.1002/dev.22135. Indice Scopus 2-s2.0-85108991539, ISSN: 00121630; PMID: 34196403. DOI: 10.1002/dev.22135. (IF 3.038)
61. Andolina D, Savi M, Ielpo D, Barbetti M, Bocchi L, Stilli D, Ventura R, Lo Iacono L, Sgoifo A, Carnevali L (2021). Elevated miR-34a expression and altered transcriptional profile are associated with adverse electromechanical remodeling in the heart of male rats exposed to social stress. Stress. 2021. Sep;24(5):621-634. Indice Scopus 2-s2.0-85110053468; ISSN: 10253890; PMID: 34227918. DOI: 10.1080/10253890.2021.1942830. (IF 3.493)
62. Lo Iacono L, Mancini C, Babicola L, Pietrosanto M, Di Segni M, D'Addario SL, Municchi D, Ielpo D, Pascucci T, Cabib S, Ferlazzo F, D'Amato FR, Andolina D, Helmer-Citterich M, Cifani C, Ventura R (2021). Early life adversity affecting the attachment bond alters ventral tegmental area transcriptomic patterning and behavior almost exclusively in female mice. Neurobiology of Stress. Oct 4;15:100406.; DOI: doi.org/10.1016/j.ynstr.2021.100406. PMID: 34660854 (IF 5.441).
63. Lampis V, Ventura R, Di Segni M, Marinod C, D’Amato FR, Mascheretti S (2021). Animal models of developmental dyslexia: where we are and what we are missing. Neuroscience and Biobehavioral Reviews. 131: 1180-1197. DOI:10.1016/j.neubiorev.2021.10.022 (IF 8.989). PMID: 34699847
64. Ventura R, Cabib S, Babicola L, Andolina D, Di Segni M, Orsini C (2021). Interactions between experience, genotype and sex in the development of individual coping strategies. Frontiers in Behavioral Neuroscience. DOI: 10.3389/fnbeh.2021.785739 (IF 3.617)
65. Mercuri NB, Federici M, Rizzo FR, Maugeri L, D'Addario SL, Ventura R, Berretta N (2021). Long-term depression of striatal DA release induced by mGluRs via sustained hyperactivity of local cholinergic interneurons. Frontiers in Cellular Neuroscience. 15, 798464. DOI:10.3389/fncel.2021.798464 (IF 6.147)
66. Merone M, D'Addario SL, Mirino P, Bertino F, Guariglia C, Ventura R, Capirchio A, Baldassarre G, Silvetti M, Caligiore D (2022). A multi-expert ensemble system for predicting Alzheimer transition using clinical features. Brain Inform. Sep 3;9(1):20. doi: 10.1186/s40708-022-00168-2. PMID: 36056985; PMCID: PMC9440971. (IF 6.54)
67. Ledonne A, Massaro Cenere M, Paldino E, D’Angelo V, D’Addario SL, Casadei N, Nobili A, Berretta N, Fusco FR, Ventura R, Sancesario G, Guatteo E, Mercuri, NB (2022). Morpho-Functional Changes of Nigral Dopamine Neurons in an α-Synuclein Model of Parkinson’s Disease. Movement Disorders. DOI: 10.1002/mds.29269 (IF 10.338)
68. D’Addario SL, Municchi D, Mancini C, Ielpo D, Babicola L, Di Segni M, Lo Iacono L, Ferlazzo F, Cifani C, Andolina D, Ventura R (2023). The long-lasting effects of early life adversities are sex dependent: the signature of miR-34a. Journal of Affective Disorders (IF 6.533). DOI: 10.1016/j.jad.2022.11.035
69. Pignataro A, Krashia P, De Introna M, Nobili A, Sabetta A, Stabile F, La Barbera L, D'Addario SL, Ventura R, Cecconi F, D'Amelio M, Ammassari-Teule M. Chemogenetic rectification of the inhibitory tone onto hippocampal neurons reverts autistic-like traits and normalizes local expression of estrogen receptors in the Ambra1+/- mouse model of female autism (2023). Transl Psychiatry. Feb 20;13(1):63. doi: 10.1038/s41398-023-02357-x. PMID: 36804922; PMCID: PMC9941573.
70. Garofalo S, Cocozza G, Mormino A, Bernardini G, Russo E, Ielpo D, Andolina D, Ventura R, Martinello K, Renzi M, Fucile S, Laffranchi M, Mortari EP, Carsetti R, Sciumè G, Sozzani S, Santoni A, Tremblay ME, Ransohoff RM, Limatola C (2023). Natural killer cells and innate lymphoid cells 1 tune anxiety-like behavior and memory in mice via interferon-γ and acetylcholine. Nat Commun. May 29;14(1):3103. doi: 10.1038/s41467-023-38899-3. PMID: 37248289; PMCID: PMC10227025.
71. Gigliucci V, Di Segni M, Ventura R, Battaglia M (2023 ). Editorial: Long-term effects of early-life manipulations: risks and advantages for neurodevelopment. Front Cell Neurosci. Apr 20;17:1193912. doi: 10.3389/fncel.2023.1193912. PMID: 37153638; PMCID: PMC10158931.
72. Babicola L, Mancini C, Riccelli C, Di Segni M, Passeri A, Municchi D, D'Addario SL, Andolina D, Cifani C, Cabib S, Ventura R (2023). A mouse model of the 3-hit effects of stress: Genotype controls the effects of life adversities in females. Prog Neuropsychopharmacol Biol Psychiatry. Dec 20;127:110842. doi: 10.1016/j.pnpbp.2023.110842. Epub 2023 Aug 21. PMID: 37611651. (IF 5.201)
73. Ielpo D, Guzzo SM, Porcheddu GF, Viscomi MT, Catale C, Reverte I, Cabib S, Cifani C, Antonucci G, Ventura R, Lo Iacono L, Marchetti C, Andolina D (2023). GABAergic miR-34a regulates Dorsal Raphè inhibitory transmission in response to aversive, but not rewarding, stimuli. Proc Natl Acad Sci U S A. Aug 8;120(32):e2301730120. doi: 10.1073/pnas.2301730120. Epub 2023 Jul 31. PMID: 37523544; PMCID: PMC10410731.
74. Passeri, A., Municchi, D., Cavalieri, G., Babicola L, Ventura, R*., Di Segni, M*. (2023) Linking drug and food addiction: an overview of the shared neural circuits and behavioral phenotype. Frontiers in Behavioral Neuroscience, 2023, 17, 1240748
* corresponding author
75. Pursey K, Babicola L, Ventura R, Di Segni M. Editorial: Dysfunctional motivation in eating behaviors: a complex gene x environment interplay. Front Behav Neurosci. 2024 Feb 9;18:1367256. doi: 10.3389/fnbeh.2024.1367256. PMID: 38405038; PMCID: PMC10885132.
76. Ventura R, Di Segni M, Santos M, Agustín-Pavón C, Torres-Pérez JV. Editorial: Long-lasting neurobehavioral effects of early-life events. Front Neurosci. 2024 Nov 19;18:1509723. doi: 10.3389/fnins.2024.1509723. PMID: 39628655; PMCID: PMC11611890.
77. Mancini C, Babicola L, Chila G, Di Segni M, Municchi D, D'Addario SL, Spoleti E, Passeri A, Cifani C, Andolina D, Cabib S, Ferlazzo F, Iosa M, Rossi R, Di Lorenzo G, Renzi M, Ventura R. Secure attachment to caregiver prevents adult depressive symptoms in a sex-dependent manner: A translational study. iScience. 2024 Nov 21;27(12):111328. doi: 10.1016/j.isci.2024.111328. PMID: 39758994; PMCID: PMC11700650.
78. Garofalo S, Mormino A, Mazzarella L, Cocozza G, Rinaldi A, Di Pietro E, Di Castro MA, De Felice E, Maggi L, Chece G, Andolina D, Ventura R, Ielpo D, Piacentini R, Catalano M, Stefanini L, Limatola C. Platelets tune fear memory in mice. Cell Rep. 2025 Feb 3;44(2):115261. doi: 10.1016/j.celrep.2025.115261. Epub ahead of print. PMID: 39903668.
Book Chapters (English)
1. Ventura R, Latagliata EC, Patrono E, Di Segni M, Puglisi-Allegra S. (2013). Food seeking in spite of harmful consequences in: Animal Models of Eating Disorders (Book chapter). Neuromethods 74 , 235-254, Springer Protocols, Humana Press; edited by Nicole M. Avena. Indice Scopus 2-s2.0-84868537182, ISSN: 08932336; DOI: 10.1007/978-1-62703-104-2_14
2. Ventura R, Babicola L, Andolina D, Patrono E. Di Segni M (2021). Food seeking in spite of harmful consequences in: Animal Models of Eating Disorders (Book Chapter). Neuromethods, 161, 161, pp. 25-56. (Second Edition) Springer Protocols, Human Press; edited by Nicole M Avena. Indice Scopus: 2-s2.0-85093104948, ISSN: 08932336; DOI: 10.1007/978-1-0716-0924-8_3
Book Chapters (Italian)
1. Andolina D, Lo Iacono L, Ventura R (2020). I modelli animali per lo studio della depressione in: Manuale di Neuroscienze Psichiatriche e Computazionali (Book Chapter; a cura di Paolo Brambilla; ed. Minerva Medica).
2. Ventura R, Andolina D, Di Segni M (2023). Genetica ed Epigenetica del trauma in: Trauma e psicopatologia (Book chapter; a cura di Stefano Vicari; ed. Erickson).