Ritratto di sergio.valente@uniroma1.it

Si riavvisano gli studenti che le lezioni per il Corso di Analisi Chimico-Farmaceutica e Tossicologica I (A-L, CTF, 2 anno)

inizieranno il giorno giovedì 05 ottobre alle ore 09:00 in aula 8 (Ex Ing, CU034) e proseguiranno per tutto il semestre secondo l'orario seguente:

lezioni: lunedì ore 13-15 Ex Ing (CU034), mercoledì ore 11-12 aula B PDT (CU018), gio ore 9-11 Ex Ing (CU034).

 

A presto

 

Cordiali saluti

Il docente

 

 

Insegnamento Codice Anno Corso - Frequentare Bacheca
TIROCINIO PRATICO VALUTATIVO AAF2380 2023/2024
TIROCINIO AAF1068 2023/2024
CHIMICA FARMACEUTICA E TOSSICOLOGICA I 1022641 2023/2024
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2023/2024
CHIMICA FARMACEUTICA E TOSSICOLOGICA I 1022641 2023/2024
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2023/2024
TIROCINIO AAF1068 2022/2023
CHIMICA FARMACEUTICA E TOSSICOLOGICA I 1022641 2022/2023
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2022/2023
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2021/2022
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2020/2021
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2019/2020
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2018/2019
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2017/2018
ANALISI CHIMICO FARMACEUTICA E TOSSICOLOGICA I 1022761 2016/2017

Il docente accetta richiesta di ricevimento con gli studenti previa mail

Personal information
Name: Sergio Valente
Work address: Piazzale Aldo Moro 5, 00185, Rome (Italy)
Phone number (Lab): 0649913593-0649913976
Phone number (Office): 0649913724
E-mail address: sergio.valente@uniroma1.it
Education
March 2007
phD Pasteur Science , at Department of Drug Chemistry and Technologies, Sapienza , University of Rome;
March 2003
University degree in Pharmacy 110/110 cum laude at the above mentioned Department.
Reasearch experiences
From March 2020: Associate Professor in Medicinal Chemistry at Department of Drug Chemistry and Technologies, Sapienza University of Rome, Italy;
From October 2011 to March 2020: Assistant Professor in Medicinal Chemistry at Department of Drug Chemistry and Technologies, Sapienza University of Rome, Italy;
July-2009-May 2011: Post-doc position (REDCAT, Marie Curie project, [European Community's] Seventh Framework Programme [FP7/2007-2013], Grant Agreement No. 215009), LIMBP, Université de la Lorraine-Metz, France.
April 2007-June 2009: contract with Sapienza University for research activity at the Department of Drug Chemistry and Technologies, Sapienza , University of Rome.
Main research activity
Design, synthesis and development of small epigenetic modulators of HDACs, SIRTs, HMTs, KDMs, DNMTs) for a new approach to anticancer chemotherapy, neurodegenerative and metabolic pathologies, anti-parasitic treatment.
Abilitations
From July 2007 National Qualification for Pharmacist profession and from February 2022 National Scientific Qualification (ASN, MIUR) for Full Professor Position.
Teaching Activity (Faculty of Pharmacy and Medicine, Sapienza University of Rome, Italy).
From 2022 Holder of the course "Medicinal and Toxicological Chemistry I", III year of master degree in CTF (Latina)
From 2015 Holder of the course Chemical-Pharmaceutical and Toxicological Analysis I , II year of master degree in CTF; holder of the course 2012-2013, 2013-2014 and 2014-2015 Chemical-Pharmaceutical and Toxicological Analysis , II year of master degree in Pharmacy; holder of the course 2011-2012 Laboratory of Extractive and Synthetic Preparation of Drugs , V year of master degree in CTF (Pharmaceutical Chemistry and Technology; member of examination committee, also for Master Degree, integrative lectures and assistance for students; d) tutoring for graduating and PhD students in Medicinal Chemistry.
Congress Communications (oral and posters)
10 oral communications and more than 100 poster communications at National and International Congresses in Medicinal Chemistry.
Awards
Paestum (SA), 11 September 2017, National Prize for Medicinal Chemistry Research received by Medicinal Chemistry Division of Italian Chemical Society.
Technical skills and competences
Advanced and microwave-assisted organic synthesis. Molecular modelling. Windows Vista, XP 2003, 2007, 2010, Windows 7-10, ISIS Draw, Chem Bio Draw 2013, MS Office, Spectrometry analysis (1H-NMR, 13C-NMR, Mass).
Grants
Project Title: Development of novel dual-targeting epigenetic modulators for novel epi-polypharmacological cancer treatment , AIRC Foundation 2021
Position in project: Principal Investigator.
Total financing: 342.000 Euro
Project Title: Mechanistic understanding of NADPH oxidases and their roles in ROS biology , PRIN-MIUR 2020
Position in project: Unit s Coordinator
Total financing: 215.574 Euro
Project Title: Design and biological evaluation of novel epigenetic dual-targeting modulators to fight cancer , Ateneo Sapienza Project
Position in project: Principal Investigator
Total financing: 48000 Euro
Project Title: Design, synthesis, anticancer evaluation of novel irreversible as well as reversible LSD1 inhibitors and development of probes for chemoproteomics of LSD1 , Ateneo Sapienza Project
Position in project: Principal Investigator
Total financing: 8000 Euro
Project Title: Anti-Parasitic Drug Discovery in Epigenetics , European Community, European Project EC-GA N°602080; WORK PACKAGE 4, 6, 7-A-PARADDISE
Position in project: Collaborator
Total financing: 284016 Euro
Project Title: Enhancer of Zeste Homolog 2 inhibitors: a novel strategy anticancer therapy , Ateneo Sapienza Project
Position in project: Collaborator
Total financing: 15000 Euro
Project Title: Regolazione dell'espressione di citochine infiammatorie nel tessuto periprotesico di protesi mammarie siliconiche mediante impiego di inibitori delle istone deacetilasi in un modello sperimentale murino , Ateneo Sapienza Project
Position in project: Collaborator.
Total financing: 33946 Euro
Project Title: Novel Probes for Sirtuin Enzymes: a Medicinal Chemistry/Chemical Biology Approach , Ateneo Sapienza Project
Position in project: Collaborator.
Total financing: 40000 Euro
Project Title: A BLUEPRINT of Haematopoietic Epigenomes ; European Community, European Project N° 282520; WORK PACKAGE 15, BLUEPRINT
Position in project: Collaborator.
Total financing: 242379.6 Euro

Reviewer activity
Journal of Medicinal Chemistry, European Journal of Medicinal Chemistry, Current Topics in Medicinal Chemistry, Expert Opinion on Drug Discovery, Expert Opinion on Therapeutics Patents, Pharmacological Research, Frontiers in Pharmacology, Autophagy, Oxidative Medicine and Cellular Longevity, Aging and Disease, Scientific Reports, Autophagy, Tetrahedron Letters.
Scientific Publications
Author/Co-Author of 147 scientific papers; H-Index: 44, total citations: 5553.