Mathematical Models in Biology

Course objectives

General goals. This course is devoted to mathematical modeling of biological phenomena. Starting from discrete models (as logistic map, fractals, cellular automata), passing through the development of simple differential population models (as Malthusian model, predator-prey, evolutionary games) up to stochastic models (genetics), the course will provide mathematical fundamentals to understand the bases of modeling in biology. Moreover, at the same time, students are supposed to learn not only general facts but also to appreciate to what extent correct models of phenomena can give information to laws that govern them. Specific goals. The main goal of the course is to acquire, in practice, the "scientific method" (observation and data collection, theoretical description of phenomena main characteristics, predictions). Starting, in particular, from a certain number of biological examples, the course aims to show how to describe mathematically the most relevant aspects of each phenomenon and how to make predictions by using this description. An interesting consequece of this approach is that a deeper analysis of the model can often generate new questions on biological phenomena. By using this method the student undestand, often for the first time, that mathematics (calculus, statistics and probability) can be used for very interesting purposes. These results can be obtained not only by means of lessons and seminars, but also by reading selected papers that can be discussed in the classroom. These papers, with the slides of lessons and notes, can be downloaded from elearning website. In the final exam students can also submit a short seminar whose subject is not included in the program: this allows the teacher to verify student autonomy and skill. A) Knowledge and understanding - knowing and understanding a mathematical model, through its predictive properties - comprehension of the "scientific method" (observation and data collection, theoretical description of phenomena main characteristics, predictions) - comprehension of the descriptive and interpretative power of mathematics - comprehension of the main mathematical methods useful in biological sciences B) Applying knowledge and understanding - be able to use the specific terminology - be able to identify the right methods to comprehend the problem under examination - be able to extract the information of biological interest from a mathematical C) Making judgements - critical thinking through the study of a mathematical model, in order to understand its applicability limits - learning by questioning D) Communication skills -be able to communicate what has been learned during the oral exam E) Learning skills - learning the specific terminology - be able to make the logical connections between the topics covered - be able to identify the most relevant topics

Channel 1
GIANLUCA PANATI Lecturers' profile

Program - Frequency - Exams

Course program
Tentative programme of the course: 1. Introduzione 2. Il modello logistico discreto 3. Il modello ed i numeri di Fibonacci 4. Il modello logistico continuo 5. Altre applicazioni della crescita esponenziale 6. Altre applicazioni semplici del modello logistico 7. Modelli con ritardo 9. Popolazioni interagenti
Prerequisites
Students are assumed to be familiar with the content of a standard course of Mathematics for the Bachelor Program, as e.g. "Matematica e Statistica" for the Bachelor program in Scienze Ambientali or "Calcolo e Biostatistica" for the Bachelor program in Scienze Biologiche, or any other equivalent course. In particular, some basic tools of calculus will be reviewed during the first week of the course, including: - differential calculus (derivatives, search for stationary points,....) - integral calculus - basics of linear algebra (matrices and all that).
Books
The main textbook, whose first 9 or 10 chapters will be explained during the course, is Giuseppe Gaeta *Modelli Matematici in Biologia* Springer Science & Business Media, 2007 - 304 pagine Further bibliographic material will be provided through the e-learning page of the course.
Frequency
Attendance to the lectures is not mandatory but strongly recommended.
Exam mode
The exam consists of an interview on the most relevant topics of the course. To be admitted to the interview the student is asked to present the solution to 3 selected problems ("starred problems"), chosen among those proposed by the lecturer during the course. The interview will initially be focused on the solution to one of these problems. The successful student will be able to illustrate theoretical concepts and mathematical proofs discussed and explained during the course. The student will be asked to apply the methods learned during the course to examples and situations similar to those that were discussed during the course. The evaluation will take into account: - correctness and completeness of the concepts illustrated by the student; - clarity and rigor of presentation; - analytical development of the theory; - problem-solving skills. To achieve a score of 30/30 cum laude, the student must demonstrate that she/he has acquired excellent knowledge of all the topics covered during the course, being able to link them in a logical and coherent way, and she/he is moreover able to apply such methods to problems (slightly) different than those presented in the course.
Lesson mode
Lectures on the theoretical concepts with classroom exercises
  • Lesson code1055458
  • Academic year2025/2026
  • CourseEcobiology
  • CurriculumBiologia ed ecologia marina
  • Year1st year
  • Semester2nd semester
  • SSDMAT/07
  • CFU6