CARMINE SAVOIA

Link Lezione Endocardite Prof Savoia_IV Anno

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CURRICULUM VITAE
CARMINE SAVOIA MD FAHA FESC

• PERSONAL INFORMATION
Date of birth: January 16th, 1971

• CURRENT POSITIONS
•Full Professor of Internal Medicine
Clinical and Molecular Medicine Department – Faculty of Medicine and Psychology – Sapienza University of Rome, Italy
• Director, Internal Medicine of Complexity Program Unit
Sant’ Andrea University Hospital – Faculty of Medicine and Psychology – Sapienza University of Rome, Italy
• Director, Vascular Pathophysiology Laboratory
Clinical and Molecular Medicine Department – Sapienza University of Rome, Italy

• EDUCATION
2001: Board Certification in Internal Medicine, Sapienza University of Rome, Italy
1997–2001: Residency in Internal Medicine, I Clinica Medica, Sapienza University of Rome, Italy
1995: Medical Degree Magna cum Laude, University “Federico II” of Naples, Italy

• HONORS and FELLOSHIP
FAHA – Fellow of the American Heart Association (since 2012)
FESC – Fellow of the European Society of Cardiology (since 2019)

• ACADEMIC POSITIONS
2022–present: Full Professor of Internal Medicine, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant’Andrea University Hospital, Sapienza University of Rome, Italy
2014–present: Visiting Professor (Research), Institute of Cardiovascular and Medical Sciences – University of Glasgow, United Kingdom
2007–2022: Associate Professor of Cardiology, Department of Clinical and Molecular Medicine, Faculty of Medicine and Psychology, Sant’Andrea University Hospital, Sapienza University of Rome, Italy
2002–2007: Research Fellow, Experimental Hypertension Laboratory, CIHR Multidisciplinary Research Group on Hypertension; Hypertension Clinic, Clinical Research Institute of Montreal, Université de Montréal, and Lady Davis Institute for Medical Research, McGill University, Montreal, Canada
2002–2004: Research Fellow, Department of Experimental Medicine and Pathology, Sapienza University of Rome

• CLINICAL RESPONSABILITIES
2025–present: Director, Internal Medicine of Complexity Program Unit, Sant’ Andrea University Hospital, Sapienza University of Rome
2023–2024: Consultant Physician in Internal Medicine, Internal Medicine Division, Sant’ Andrea University Hospital, Sapienza University of Rome
2009–2023: Consultant Cardiologist, Division of Cardiology, Sant’Andrea University Hospital, Sapienza University of Rome:
- Cardiovascular consultation service for Internal Medicine patients
- Cardiovascular consultation service for the Emergency Department
- Management of inpatient and outpatient cardiovascular care

• ACADEMIC LEADERSHIP APPOINTMENTS
2025–present: Vice-Dean for Health Professions, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
2025–present: Vice-Director, Residency Program in Internal Medicine, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
2024–present: Vice-President, Degree Program in Medicine and Surgery (Sant’Andrea Campus), Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
2024–2026: Faculty Representative for Disability and Specific Learning Disorders (SLD) in the Medical Area, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
2023–present: President, International Bachelor’s Degree Program in Nursing, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
2023–2024: Chair, Monitoring Committee, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
2015–2024: Member, Monitoring Committee, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
2015–2023: Vice-President, International Bachelor’s Degree Program in Nursing, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy

• PROFESSIONAL SOCIETY LEADESRSHIP AND OTHER APPOINTMENTS
2022 Oct – 2024 Oct: President, European Council for Cardiovascular Research (ECCR)
2021 Sept – 2022 Oct: President-Elect, ECCR
2016–2024: Member, Executive Committee, ECCR
2017–2022: Member, Executive Committee, Italian Society of Hypertension
2014–2017: Member, Study Group on Micro- and Macrocirculation, Italian Society of Hypertension (SIIA)
2014–2017: Chair, Lazio Regional Branch, Italian Society of Hypertension
2009–2010: Deputy Member of the Board, Italian Society of Hypertension – Lazio Branch

• RESEARCH
o CURRENT SCIENTIFIC INTEREST
Clinical and experimental hypertension; molecular and vascular mechanisms underlying cardiovascular remodeling; vascular aging and arterial stiffness; renin–angiotensin–aldosterone system signaling in vascular disease; vascular toxicity of VEGFR inhibitors; precision cardiovascular medicine; cardiometabolic risk assessment and prevention; early detection, prevention, and treatment of heart failure across the cardiometabolic continuum.
o COLLABORATIONS
- Institute of Cardiovascular and Medical Sciences, University of Glasgow, UK
- Lady Davis Institute for Medical Research, McGill University, Montreal, Canada
- University of Southern Denmark, Institute of Molecular Medicine / Department of Cardiovascular and Renal Research
- Center for Cardiovascular Research, Charité–Universitätsmedizin Berlin, Germany
- MDC Max Delbrück Center for Molecular Medicine, Berlin-Buch, Germany
- Department of Experimental Medicine and Biochemical Sciences, University of Tor Vergata
- Department of Histology and Medical Embryology, Sapienza University of Rome
o RESEARCH GRANTS
- 2025 Research Project: BIOMIND - Development of advanced diagnostic assays based on new BIOmarkers from liquid biopsy. A generalized workflow for connecting Medical Research to product INDustrialization Advanced Oncological Diagnostic Hub based on Radio-Bio-Genomic data AI-integrated Platform.
(Role: Co-investigator)
- 2025 Sapienza University Research Projects - Effectiveness of novel antidiabetic agents in reducing early hepatic and cardiovascular damage via inflammatory modulation in individuals with type 2 Diabetes (T2D) and metabolic dysfunction-associated steatotic liver disease (MASLD).
(Role: Co-investigator)
- 2023 Sapienza University Research Projects (Medium-size Scientific Equipment) - Cell metabolism profiling through Seahorse technology: a common key to understand mechanisms of dysregulation and to develop molecular targeted therapies.
(Role: Co-investigator)
- 2022 Sapienza University Research Projects - Ruolo dell'attivazione autonomica simpatica, dell'infiammazione e dell'attivazione piastrinica in pazienti con sindrome coronarica acuta a coronarie indenni.
(Role: Principal Investigator)
- 2021 Sapienza University Research Projects - High-field MRI advanced neuroimaging characterization of cerebrovascular damage in a mouse model of hypertension-induced cognitive impairment.
(Role: Co-investigator)
- 2020 Sapienza University Research Projects H2020 - Hypoxic ischemic brain injury pathophysiology: a deeper understanding of hypoxia-resilient neurons and microvasculature modulation for post-cardiac arrest recovery (HIBImod).
(Role: Co-investigator)
- 2019 Sapienza University Research Projects - Role of CD44 splicing variants in prostate and testis cancers as potential markers for monitoring stem cell plasticity.
(Role: Co-investigator)
- 2018 Sapienza University Research Projects - Oxidative stress and vascular inflammation in hypertension induced by VEGF inhibitors: role of p66Shc.
(Role: Principal Investigator)
- 2018 Sapienza University Research Projects (Big-size Scientific Equipment) - Integrated Platform for phenotypic, functional, and molecular profiles of mouse models.
(Role: Co-investigator)
- 2017 Sapienza University Research Projects - Hypertension and cardiovascular fibrosis: role of p66Shc in aldosterone-induced fibrosis.
(Role: Principal Investigator)
- 2016 Sapienza University Research Projects - Ruolo del peptide Natriuretico Atriale nella regolazione del processo di autofagia. Implicazioni nelle patologie cardiovascolari.
(Role: Co-investigator)
- 2015 PRIN 2015 Research Grant, Italian Ministry of Education, University and Research (MIUR) - “Defective tissue repair in metabolic disorders: untangling its role and key mechanisms for novel therapeutic approaches”
(Role: Principal Investigator of the Local Research Unit)
- 2015 Fondazione Roma Biomedical Research Grant - “Analysis of the authophagy-dependent regulation of lymphocyte homeostasis and autophagy manipulation in atherosclerosis”
(Role: Head of Unit)
- 2015 Sapienza University Research Projects - Etiopathogenetic relevance of AMPK/SIRT1/PGC-1a/UCP2 pathway in hypertension and aging related vascular damage in an animal model of complex human disease.
(Role: Co-investigator)
- 2014 Sapienza University of Rome Grant for Scientific Collaborations - Inibitori del VEGFR ed ipertensione arteriosa
(Role: Project Leader)
- 2014 Research Grant from Daiichi Sankyo Italia - Role of the Renin–Angiotensin System in Modulating Transglutaminase 2–Mediated Vascular Remodeling and Dysfunction in Hypertensive Rats: Implications for Angiotensin Receptor Blockade.
(Role: Principal Investigator)
- 2014 Scientific Research Grant from Stroder - “Ivabradine on ventricular performance and vascular compliance in patients with post-ischemic ventricular dysfunction”
(Role: Principal Investigator)
- 2014 Sapienza University Research Projects - Molecular basis of acute cardiovascular events: role of mitochondrial dysfunction.
(Role: Co-investigator)
- 2013 Sapienza University Research Projects - Characterization of the vascular properties of a molecular variant of atrial natriuretic peptide as a novel risk factor for acute cardiovascular events.
(Role: Co-investigator)
- 2012 Sapienza University Research Projects - “Regulation of prostate carcinogenesis and tumor progression by microRNAs: Toll-like Receptors and Intercellular Communication through Exosomes”
(Role: Co-investigator)
- 2010: Sapienza University of Rome Research Grant (“Ricerche Universitarie”) - “Role of angiotensin II- induced modulation of transglutaminase 2 on vascular remodeling in essential hypertension”
(Role: Principal Investigator)
- 2009: Scientific Research Grant from Novartis Pharma - “Renin Inhibition and Remodeling of Resistance Arteries in double Transgenic Rats”
(Role: Principal Investigator)
- 2009: Sapienza University of Rome Research Grant (“Ex Quota di Facoltà”) - “Role of ACE2/Angiotensin-(1-7)/Mas Receptor activation on resistance arteries remodeling”
(Role: Principal Investigator)
- 2008: Sapienza University of Rome Research Grant (“Ex Quota di Facoltà”) - “Renin Inhibition and Remodeling of Resistance Arteries”
(Role: Principal Investigator)

• TEACHING AND MENTORING
o PhD PROGRAM FACULTY APPOINTMENTS
- Digital Cardiovascular Medicine, Pathology, and Cutting-Edge Therapeutics (International PhD Program)
- Pre-clinical Research and Innovative Diagnostic–Therapeutic Applications
- Biomedical and Surgical Sciences
- Experimental Medicine
o FACULTY APPOINTMENTS IN POSTGRADUATE MEDICAL SPECIALTY TRAINING PROGRAMS
- Internal Medicine, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
- Emergency and Urgency Medicine, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
- Geriatrics Residency Program, Umberto I University Hospital & Sant’Andrea University Hospital, Faculty of Medicine and Dentistry, Sapienza University of Rome, Italy
- Cardiovascular Medicine, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
- Respiratory Diseases, Umberto I University Hospital & Sant’Andrea University Hospital, Faculty of Medicine and Dentistry, Sapienza University of Rome, Italy
- General Surgery, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
- Clinical Pathology and Clinical Biochemistry, Sant’Andrea University Hospital, Faculty of Medicine and Psychology, Sapienza University of Rome, Italy
o TEACHING APPOINTMENTS IN DEGREE PROGRAMS
- Degree Program in Medicine and Surgery (Sant’Andrea Campus), Faculty of Medicine and Psychology, Sapienza University of Rome, Italy: 2nd, 3rd, and 6th Year
- International Degree Program in Medicine and Surgery, Sapienza University of Rome, Italy: 2nd and 4th Year
- International Bachelor’s Degree in Nursing, Sapienza University of Rome, Italy: 2nd and 3rd Year
- Bachelor's Degree in Dietetics (qualifying for the healthcare profession of Dietitian) - Sapienza University of Rome, Italy: 3rd Year

• EDITORIAL APPOINTMENTS
- Editorial Board Member: Hypertension (IF 8.2)
- Associate Editor: Frontiers in Physiology – Clinical and Translational Physiology (IF 3.4)
- Deputy Editor: High Blood Pressure and Cardiovascular Prevention (IF 2.9)
- Editorial Board Member: International Journal of Molecular Sciences (IF 4.9)
- Editorial Board Member, Current Hypertension Reviews (5 years IF 2.5)

• PUBLICATIONS AND BIBLIOMETRIC INDICATORS:
Author of more than 100 full-length peer-reviewed publications in international journals.
H-Index: 35 (Scopus)
Total citations: 4737 (Scopus)
ORCID: 0000-0002-2296-1959

• SCIENTIFIC COMMITTEES, GRANT REVIEW, AND PEER-REVIEW ACTIVITIES
- 2025 – Scientific Reviewer for Research Proposals, Croatian Science Foundation (HRZZ)
- 2024 – Reviewer of Research Projects, Austrian Science Fund (FWF)
- 2018–2020 – Member of Evaluation Panel CE14 – Physiologie et physiopathologie, French National Research Agency (ANR)
- 2014–2016 – Member, National Committee for Confirmation of Tenured Assistant Professors in Cardiology, Italian Universities
- 2012–2013 – Referee for National (Italian) Grant Applications and Scientific Research Products
- VQR 2004–2010 & 2011–2014 – Referee for the Evaluation of Scientific Research Outputs, Italian National Research Quality Assessment (VQR)
- 2010 – Reviewer, Boston Area Diabetes Endocrinology Research Center Pilot and Feasibility Grant (BADEREC 2010)

• LECTURES AND SCIENTIFIC MEETINGS
Since 1998, invited speaker, session chair, and faculty member at leading national and international scientific meetings in hypertension and cardiovascular medicine, including conferences of the American Heart Association (AHA), High blood Pressure Research Council - AHA, European Society of Hypertension (ESH), European Society of Cardiology (ESC), International Society of Hypertension (ISH), Canadian Hypertension Society, InterAmerican Society of Hypertension, Italian Society of Hypertension (SIIA), Italian Society of Cardiology (SIC), Italian Society of Internal Medicine (SIMI) and other national and international scientific societies.

• AWARDS AND HONORS
Recipient of multiple competitive research grants, fellowships, and scientific awards from national and international scientific societies and academic institutions in recognition of contributions to cardiovascular and hypertension research.
Selected Awards and Honors:
- 2001 Fellowship and Grant for Cardiovascular Research from Italian Society of Hypertension (SIIA).
- 2004 Pfizer Canada Award Research Day, Clinical Research Institute of Montreal, University of Montreal, Canada;
- 2005: New Investigator Merit Award, Interamerican Society of Hypertension – supported by a grant of AHA-Council for High Blood Pressure Research;
- 2006: New Investigator Award for US Fellows – supported by an educational grant from CV Therapeutics, AHA-Council for High Blood Pressure Research”
- 2006: Young investigator award” from Italian Society of Cardiology;
- 2007: New Investigator Travel Award-supported by an educational grant from the Inter-American Society of Hypertension, Council for High Blood Pressure AHA and the National Heart, Lung, and Blood Institute;
- 2007: Sarah Strathmore Award: Cardiovascular Research Day, McGill University, Montreal, Canada;
- Recipient of multiple awards for scientific presentations at annual meetings of American Society of Hypertension; Canadian Society of Hypertension; Société Québécoise d'Hypertension Arterielle; International Society of Hypertension; Italian Society of Hypertension.

Rome, July 4th, 2026

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