Notizie
Corso di Laurea Magistrale in Medicina e chirurgia "B"
Insegnamento: Patologia e Fisiopatologia Generale I - Patologia Generale
Corso di Laurea Magistrale in Biotecnologie mediche
Insegnamento: Patologia Molecolare e Cellulare I
Corso di Laurea Magistrale in Scienze delle Professioni Sanitarie Tecniche Diagnostiche
Insegnamento: Metodologia di Ricerca
Moduli: Patologia Generale e Statistica Sanitaria
Il materiale è disponibile nella Classroom dell' insegnamento.
Corso di Laurea in Tecniche di Radiologia Medica, per Immagini e Radioterapia
Insegnamento: Basi Cellulari e Molecolari della Vita
Modulo: Patologia Generale
Il materiale è disponibile nella Classroom dell' insegnamento.
Ricevimento: Previo appuntamento concordato tramite e-mail: zeinmersini.besharat@uniroma1.it
Orari di ricevimento
Previo appuntamento concordato tramite e-mail: zeinmersini.besharat@uniroma1.it
Curriculum
WORK EXPERIENCE
2023 - present: Tenure Track Researcher (RTT), Department of Experimental Medicine, Sapienza University of Rome
2020 – 2023: RTD A Researcher, Department of Experimental Medicine, Sapienza University of Rome
2020 – present: Faculty Member of PhD in “Network Oncology and Precision Medicine”, Sapienza University of Rome
31/05/2021: Awarded the National Scientific Qualification for Associate Professor for the SC 06/A2, SSD MED/04 of the Call 2018-2020
2018 – 2020: Post-doctoral researcher at the University of Siena and Sapienza University
2016 – 2018: Post-doctoral researcher at the Department of Experimental Medicine, Sapienza University of Rome
EDUCATION AND TRAINING
2013 – 2016: PhD in Molecular Medicine
2013: Diploma of Electrical and Computer Engineering, Master of Engineering Communications with a focus on Biomedicine
WORK ACTIVITIES
Research projects
Bioinformatics analyses using omics tools: Development of large-scale approaches for expression data analyses from different platforms -next generation sequencing and assays.
Molecular oncology: Characterization of the molecular events involved in tumorigenesis mainly focusing on solid tumors and deregulated pathways.
Hedgehog/Gli signaling pathway: Analysis of dysregulated mechanisms of the Hedgehog/Gli signaling pathway involved in neoplastic diseases.
Oncosuppressor and oncogenes: Identification of novel molecules as oncosuppressor or oncogenes.
MicroRNAs and Epigenetic regulation: Identification of epigenetic networks including microRNAs and long non-coding RNAs in tumors.
Circulating biomarkers: Analysis and discovery of circulating biomarkers (mainly microRNAs and cfDNA) in cancer.
Tumors and cancer treatments: Medulloblastoma, neuroblastoma, gliomas, lung, colorectal, thyroid cancers, melanoma, chemoresistance and immunotherapy.
Awards
Winner of Minerva Research award III Edition for research on the role of microRNAs in cancer, Foundation Roma Sapienza. 01.12.2021.
Winner of Post-doctoral Fellowship Fondazione Umberto Veronesi year 2022. 26.11.2021.
Three-year scholarship for the completion of PhD in Molecular Medicine, Sapienza University of Rome. 2013-2016.
Collaborations
Participation in Italian and International research groups
Italian: Sapienza University (Dep. of Radiological, Oncological and Pathological Science, Dep. of Drug Chemistry and Technologies, Dep. of Molecular Medicine, Dep. of Informatics, Dep. of Computer, Control and Management Engineering, Dep. of Translational and Precision Medicine), Ospedale Pediatrico Bambino Gesù, University of Siena
International: David H. Koch Institute for Integrative Cancer Research MIT Cambridge (MA) USA, Heidelberg University Germany, University of Bern Switzerland
Editorial activity as Editor
International Scientific Board Member as Guest Editor of Special Issue “Molecular Biomarkers in Cancer and Metabolic Disease in the International Journal of Molecular Sciences. 2019 – present. IF 6.20
International Scientific Board Member as Guest Editor of Special Issue “Signalling pathways in Metabolic Diseases and Cancer” in Cancers. 2019 – present. IF 6.57
“Circulating Biomarkers in Cancer: Towards Personalized Precision Medicine” in Frontiers in Cell and Developmental Biology. 2023– present. IF 6.08
Referee of International Scientific Journals
BMC Cancer, Cancer Management and Research, International Journal of Molecular Sciences, OncoTargets and Therapy, Frontiers Cell And Developmental Biology, Diagnostics, Journal of Immunology Research, Cancers, Journal of Personalized Medicine, Biomedicines, Frontiers Pharmacology, Journal of Translational Medicine
Member of Expert Peer Reviewers for Italian Scientific Evaluation (REPRISE), Italian Ministry of Education, University and Research
International
2019 – Present: Member of the European Association for Cancer Research (EACR), Member ID EACR27439
memberships 2014 – Present: Member of the European SIOP-LGG preclinical working group (preclinical working group on low grade glioma, LGG, of the International Society of Pediatric Oncology, SIOP)
Grants
“Evaluation of circulating microRNAs in medulloblastoma as prognostic biomarkers”. Sapienza University Research Grants 2019, Duration: 1 year, Principal Investigator: Besharat Zein Mersini. 3.000€.
“Circulating microRNAs and DNA (cfDNA) as novel biomarkers for diagnostic, prognostic and therapeutic use in Medullary Thyroid Carcinoma” AIFA, PI: Prof. Elisabetta Ferretti, 983.497,87 €. Investigator: Besharat Zein Mersini.
ADDITIONAL INFORMATION
Researcher identifiers
Scopus Author ID: 56595254100; ORCID: 0000-0003-0317-9854; ResearcherID: A-3898-2015; Google Scholar: Besharat ZM
Complete list of publications can be found at: https://www.scopus.com/authid/detail.uri?authorId=56595254100
Scientific production (first publication in 2014, reference period 2014-2022)
Total number of publications in international peer-reviewed journals: 56; Book chapters: 2
Total Impact factor (IF): 313.35 (IF publication year); 287.90 (IF 2023)
Average IF/paper: 5.59 (IF publication year); 5.14 (IF 2023)
Total Citations: 1228 (Scopus), 1549 (Google Scholar);
Average Citations per Product: 21.92
H-index: 21 (Scopus), 22 (Google Scholar)
Normalized H index*: 1.91
*H index divided by the academic seniority.