GENETICS

Course objectives

General skills The course provides students with a basic knowledge of Genetics aimed at understanding the rules of inheritance, their molecular bases, their main applications and their implications for evolution. In addition, the course will allow students to understand how genetic information is encoded at the DNA level and how the biochemical processes of the cell translate genetic information into a phenotype. The course aims to achieve these objectives through an analysis of the experimental evidences and their interpretation. Specific skills A) Knowledge and understanding -Knowledge and understanding of the characteristics of the genetic material -Knowledge and understanding of the rules of genetic transmission -Knowledge and understanding of mutations and their implications -Basic knowledge on the dynamics of genes in populations as well as on the genetic mechanisms underlying evolution B) Applying knowledge and understanding - usage of a proper genetic terminology - identification of the right procedures to solve genetic problems - formulation of hypotheses on the hereditary transmission of characters - constructing and interpreting genetic maps and genealogical trees - acquisition of conceptual tools for the genetic dissection of biological systems - utilizing basic biostatistical methodologies for data analysis and hypothesis testing C) Making judgements - Acquisition of a critical judgment capacity on solving problems of formal genetics, through the study of the evolution of the gene concept from Mendel to the present day and the detailed analysis of some fundamental experiments. - Addressing questions for the elaboration and deepening of the gained information D) Communication skills - communicating the genetic concepts acquired during the course with appropriate terminology E) Learning skills - logically connecting the acquired knowledge - identification of the most relevant topics of the issues discussed during the course

Channel 1
FIAMMETTA VERNI' Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, verified through the entrance test. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Course attendance is not mandatory but highly recommended
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 4 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hour. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests. Alternatively: written test consisting of 4 numerical exercises on the e-learning platform (60 minutes) and an oral exam on the meet platform
Bibliography
For this course no bibliography is required
Lesson mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
FIAMMETTA VERNI' Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, verified through the entrance test. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Course attendance is not mandatory but highly recommended
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 4 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hour. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests. Alternatively: written test consisting of 4 numerical exercises on the e-learning platform (60 minutes) and an oral exam on the meet platform
Bibliography
For this course no bibliography is required
Lesson mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Channel 2
LAURA FANTI Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, verified through the entrance test. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Course attendance is not mandatory but highly recommended
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 4 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hour. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests. Alternatively: written test consisting of 4 numerical exercises on the e-learning platform (60 minutes) and an oral exam on the meet platform
Bibliography
For this course no bibliography is required
Lesson mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
LAURA FANTI Lecturers' profile

Program - Frequency - Exams

Course program
The module includes 2.5 CFU of frontal teaching + 0.5 CFU of practical exercises. Attendance is not compulsory, but strongly recommended especially for the part related to the performance of numerical exercises. Structure and function of the eukaryotic chromosome (6 hours). Outline on the regulation of eukaryotic gene expression. Sex Determination. Dosage compensation (4 hours). Population genetics and evolution (5 hours). Elements of Genomics and Epigenetics (5 hours) Numerical exercises for the subjects that foresee them and laboratory sessions in which the students will deduce the transmission patterns of some Drosophila genes examining the progeny resulting from some intersections. Population genetics exercises by frequency analysis of taste genes (12 hours).
Prerequisites
The teaching of Genetics in the three-year course is in the second semester of the first year and is included among the fundamental teachings. Essential prerequisites for understanding the topics covered are a solid understanding of cell biology and basic mathematical concepts. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory instructions: Cellular biology and Histology
Books
Texts: GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA: Snustad -Simmons - EDISES
Teaching mode
The 10 hours of lectures will be held in the classroom with the use of Powerpoint files on the topics of the program The 12 hours of exercises will be carried out in an educational laboratory and in the classroom
Frequency
Class attendance is not mandatory.
Exam mode
The exam test aims to verify the level of knowledge and deepening of the topics of the program and the reasoning skills developed by the student. The evaluation is expressed in thirtieths (minimum mark 18/30, maximum mark 30/30 with honors). The exam consists of a written test and an oral exam The written exam includes 6 exercises on the main topics covered in class. Calculators are allowed. The test has a total duration of 2 hours. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the teacher in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language ownership, expository clarity and critical ability in the face of genetic problems. The time spent on the oral exam is about 20/30 minutes in total. The final grade will result from an average between the two written and oral tests.
Bibliography
All the slides of the lessons and the exercises done in the classroom are available on the e-learning website
Lesson mode
The 10 hours of lectures will be held in the classroom with the use of Powerpoint files on the topics of the program The 12 hours of exercises will be carried out in an educational laboratory and in the classroom
GIOVANNI CENCI Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, verified through the entrance test. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Course attendance is not mandatory but highly recommended
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 4 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hour. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests. Alternatively: written test consisting of 4 numerical exercises on the e-learning platform (60 minutes) and an oral exam on the meet platform
Bibliography
For this course no bibliography is required
Lesson mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
GIOVANNI CENCI Lecturers' profile

Program - Frequency - Exams

Course program
The course consists of 6 CFU hours of frontal teaching + 0.5 CFU of exercises and laboratory sessions. Lectures are not mandatory, but strongly recommended especially for the part related to the numerical exercises training. Topics: Experiments and Mendels laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair Cracking the Genetic code (3 hours). Gene regulation in prokaryotes. Lac operon (3 hours). Genetics of cancer (2 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (3hours).
Books
Suggested Text-books: GENETICS: from Formal Analysis to Genomics - Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICS: Pimpinelli- AMBROSIANA GENETICS (exercises): Elrod and Stansfields Shaum's - MCGRAWHILL PRINCIPLES OF GENETICS: Snustad -Simmons - EDISES
Channel 3
LAURA CIAPPONI Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, verified through the entrance test. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Course attendance is not mandatory but highly recommended
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 4 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hour. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests. Alternatively: written test consisting of 4 numerical exercises on the e-learning platform (60 minutes) and an oral exam on the meet platform
Bibliography
For this course no bibliography is required
Lesson mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
LAURA CIAPPONI Lecturers' profile

Program - Frequency - Exams

Course program
The course consists of 8 CFU hours of frontal teaching + 1 CFU of exercises and laboratory sessions. Lectures are not mandatory, but strongly recommended especially for the part related to the numerical exercises training. Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, which are believed ascertained by passing the entrance test In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICS: from Formal Analysis to Genomics - Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICS (exercises): Elrod and Stansfields Shaum's - MCGRAWHILL PRINCIPLES OF GENETICS: Snustad -Simmons - EDISES GENETICS. Principles of formal Analysis - Griffith -Zanichelli
Teaching mode
The course consists of: - lectures - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Lectures and labs are not mandatory, but are strongly recommended.
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 6 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hours. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor(s) in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests.
Bibliography
GENETICS: from Formal Analysis to Genomics - Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICS (exercises): Elrod and Stansfields Shaum's - MCGRAWHILL PRINCIPLES OF GENETICS: Snustad -Simmons - EDISES GENETICS. Principles of formal Analysis - Griffith -Zanichelli
Lesson mode
The course consists of: - lectures - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Channel 4
LUCIA PIACENTINI Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, verified through the entrance test. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Course attendance is not mandatory but highly recommended
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 4 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hour. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests. Alternatively: written test consisting of 4 numerical exercises on the e-learning platform (60 minutes) and an oral exam on the meet platform
Bibliography
For this course no bibliography is required
Lesson mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
LUCIA PIACENTINI Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes. Chromosomal and genome mutations. Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments. Brief description of DNA chemical properties, replication, transcription, translation and repair. Cracking the Genetic code. Structure and function of the eukaryotic chromosome. Gene regulation in prokaryotes. Lac operon. Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation. Genetics of cancer. Population genetics and evolution. Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste.
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
The course consists of: - lectures - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
the frequency is not mandatory
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 6 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 2 hours. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests.
Lesson mode
The course consists of: - lectures - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
BENIAMINO TROMBETTA Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics, verified through the entrance test. In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
Course attendance is not mandatory but highly recommended
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 4 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 1 hour. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests. Alternatively: written test consisting of 4 numerical exercises on the e-learning platform (60 minutes) and an oral exam on the meet platform
Bibliography
For this course no bibliography is required
Lesson mode
- Frontal lectures (or in streaming on the zoom platform) - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
BENIAMINO TROMBETTA Lecturers' profile

Program - Frequency - Exams

Course program
Topics: Experiments and Mendel’s laws. Genotype and phenotype. Theories of inheritance. Chromosomal bases of heredity. Mitosis and meiosis. Extensions of Mendelian genetic inheritance. Interactions between genes and among genes and environmental factors. Sex linkage. Pedigree study. Gene association and crossing-over. Genetic maps in eukaryotes and prokaryotes (30 hours). Chromosomal and genome mutations (6 hours). Structure and function of the gene: Complementation test and intragenic recombination. Benzer experiments (6 hours). Brief description of DNA chemical properties, replication, transcription, translation and repair (1 hour). Cracking the Genetic code (2 hours). Structure and function of the eukaryotic chromosome (4 hours). Gene regulation in prokaryotes. Lac operon (5 hours). Overview of the regulation of eukaryotic gene expression. Genetics of sex determination. Dosage compensation (4 hours). Genetics of cancer (2 hours). Population genetics and evolution (4 hours). Numerical exercises and laboratory sessions in which the students will decipher the transmission patterns of some Drosophila genes examining the progeny resulting from specific crosses. Population genetics exercises focused on the genetics of taste (12 hours).
Prerequisites
The course of Genetics is on first year, second semester of the three-year Biological Science degree and is included among the fundamental teachings. Essential prerequisites for understanding the topics illustrated during the course are a robust understanding of cell biology and basic concepts of mathematics In particular, the following are required: • elements of probability and algebra calculation • basic knowledge of chemistry • basic knowledge of general biology (eukaryotes and prokaryotes, cell structure, cell cycle) Preparatory exam: Cellular biology and Histology
Books
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Teaching mode
The course consists of: - lectures - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Frequency
The course consists of: - lectures - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
Exam mode
The final exam test is meant to verify the level of knowledge of the concepts acquired during the course and the reasoning skills developed by the student. The final exam consists of a written test and an oral exam The written exam consists of 6 numerical exercises covering the following topics - pedigree analysis - Mendel laws and cytogenetics - construction of genetic maps - bacterial genetics - analysis of tetrads - population genetics The test has a total duration of 2 hours. The written test aims to ascertain the student's ability to apply the acquired knowledge to solve genetic questions. The minimum suggested score for admission to the oral exam is 18/30. The oral exam consists of an interview with the instructor in order to verify the achievement of the objectives in terms of knowledge and skills acquired, as well as communication skills, language property, clarity of exposition and critical ability to solve genetic problems. The time spent for the oral exam is about 20/30 minutes. The final grade will result from an average between the written and oral tests.
Bibliography
GENETICA: dall'Analisi Formale alla Genomica- Hartwell, Hood, Goldberg, Reynolds, Silver, Veres - MCGRAWHILL GENETICA: Pimpinelli- AMBROSIANA GENETICA (esercizi): Elrod and Stansfields Shaum’s - MCGRAWHILL PRINCIPI DI GENETICA:Snustad -Simmons - EDISES
Lesson mode
The course consists of: - lectures - numerical exercises on the topics described during classes as a training for the final written test - laboratory exercises aimed at applying knowledge of the methods of gene transmission. Students learn from the lectures the fundamental principles of genetics. The exercises are aimed at self-assessment of the level of achieved learning.
  • Lesson code1011788
  • Academic year2024/2025
  • CourseBiology
  • CurriculumGenetico-molecolare
  • Year1st year
  • Semester2nd semester
  • SSDBIO/18
  • CFU6
  • Subject areaDiscipline biologiche