Curriculum
Ricercatore universitario a tempo determinato “tipo B” (RTDB) presso Sapienza Università di Roma
Dirigente Medico Universitario presso UOC Chirurgia generale e trapianti d’organo, Azienda Ospedaliero-Universitaria Policlinico Umberto I di Roma
• Luglio 2003 Conseguimento del diploma di maturità scientifica con votazione finale di 100/100, Liceo Statale Scientifico “Galileo Galilei”, Lamezia Terme (CZ)
• 28 Luglio 2009 Laurea in Medicina e Chirurgia presso “La Sapienza” Università di Roma con voto di 110/110 e lode. Tesi sperimentale dal titolo “Il trapianto di Fegato nel trattamento dell’Epatocarcinoma. Quale Futuro: Dalla ricerca all’applicazione clinica. Relatore: Prof. Massimo Rossi
• 9 Marzo 2010 Iscrizione all’Ordine Provinciale di Roma dei Medici Chirurghi e degli Odontoiatri
• 31 maggio 2016 Specializzazione in Chirurgia Generale presso “ Sapienza” Università di Roma con voto 70/70 e lode. Tesi sperimentale dal titolo: Ruolo Prognostico dei Markers Infiammatori nei pazienti trapiantati di fegato per Epatocarcinoma. Relatore Prof. Pasquale B. Berloco
• Dall’1 settembre 2016 al 31 agosto 2017 Titolare di Assegno di Ricerca valido 12 mesi presso “Sapienza” Università di Roma, Dipartimento di Chirurgia Generale e Trapianti D’organo “P. Stefanini” con progetto di ricerca “Tecniche di perfusione nel prelievo di organi addominali”.
• 7 settembre 2018 Abilitazione Scientifica Nazionale. Conseguimento Idoneità a Professore di II fascia per il settore Concorsuale (06/C1) – Settore Scientifico Disciplinare MED/18 (Chirurgia Generale)
• 26 settembre 2019 Conseguimento del titolo di Dottore di Ricerca. Dottorato in Tecnologie Avanzate in Chirurgia. 30° ciclo. Sapienza Università di Roma
PUBLICAZIONI INDEXATE (Pubmed, Scopus)
• 2009
Lai Q, Pretagostini R, Poli L, Melandro F, Ferretti S, Della Pietra F, Rossi M, Berloco PB. Delayed graft function decreases early and intermediate graft outcomes after expanded criteria donor kidney transplants. Transplant Proc. 2009 May;41(4):1145-8.
• 2010
Lai Q, Pretagostini R, Poli L, Levi Sandri GB, Melandro F, Grieco M, Spoletini G, Rossi M, and Berloco PB. Early urine output predicts graft survival after kidney transplantation. Transplantation Proceedings, 42, 1090–1092 (2010).
• 2011
Lai Q, Nudo F, Levi Sandri GB, Melandro F, Ferretti S, Grieco M, Garofalo M, Poli L, Pretagostini R, and Berloco PB. Survival after kidney transplantation does not differ with 50–59- or over 60-year-old expanded-criteria donors. Transplantation Proceedings, 2011 May;43(4):1030-2.
• 2011
Lai Q, Levi Sandri GB, Melandro F, Di Laudo M, Garofalo M, Guglielmo N, Grieco M, Di Tondo U, Rossi M, and Berloco PB. An unusual case of hepatic carcinosarcoma. Giornale di Chirurgia, G Chir. 2011 Aug-Sep;32(8-9):372-3.
• 2011
Berloco PB, Lai Q, Levi Sandri GB, Melandro F, Mennini G, Nudo F, Guglielmo N, Rossi M. Laparoscopy in solid organ transplantation: a comprehensive review of the literature. Giornale di Chirurgia, 2011 Jun-Jul;32(6-7):293-306.
• 2011
Lai Q, Mennini G, Nudo F, Levi Sandri GB, Melandro F, Guglielmo N, Berloco PB, and Rossi M. Liver transplantation for adult hepatic epithelioid hemangioendothelioma: report of 2 cases. Journal of Hepato-gastroenterology, XX, XXX (2011). En attente de publication
• 2011
Lai Q, Nudo F, Molinaro A, Mennini G, Spoletini G, Melandro F, Guglielmo N, Parlati L, Mordenti M, Ginanni Corradini S, Berloco PB, Rossi M. Does caval reconstruction technique affect early graft function after liver transplantation? A preliminary analysis. Transplant Proc. 2011 May;43(4):1103-6.
• 2011
Lai Q, Melandro F, Levi Sandri GB, Mennini G, Corradini SG, Merli M, Berloco PB, Rossi M. Use of elderly donors for liver transplantation: has the limit been reached? J Gastrointestin Liver Dis. 2011 Dec;20(4):383-7.
• 2012
Lai Q, Melandro F, Pinheiro RS, Donfrancesco A, Fadel BA, Levi Sandri GB, Rossi M, Berloco PB, Frattaroli FM. Alpha-Fetoprotein and Novel Tumor Biomarkers as Predictors of Hepatocellular Carcinoma Recurrence after Surgery: A Brilliant Star Raises Again. Int J Hepatol. 2012;2012:893103. Epub 2012 Jun 27.
• 2012
Levi Sandri GB, Lai Q, Melandro F, Guglielmo N, Garofalo M, Morabito V, Cirelli C, Lucatelli P, Di Laudo M, Rossi M, Berloco PB. Hepatic resection for giant haemangioma in a patient with a contemporaneous adult polycystic liver disease. Clin Ter. 2012;163(5):401-2.
• 2012
Novelli G, Morabito V, Lai Q, Levi Sandri GB, Melandro F, Pugliese F, Novelli S, Rossi M, Berloco PB. Glasgow coma score and tumor necrosis factor α as predictive criteria for initial poor graft function. Transplant Proc. 2012 Sep;44(7):1820-5. doi: 10.1016/j.transproceed.2012.06.038.
• 2012
Levi Sandri GB, Lai Q, Morabito V, Garofalo M, Guglielmo N, Melandro F, Di Laudo M, Montalto G, Lucatelli P, Berloco PB Later diagnosed with a neuroendocrine tumor, case report of a 60-year-old. Clin Ter. 2012;163(5):e325-6.
• 2013
Lattanzi B, Lai Q, Guglielmo N, Giannelli V, Merli M, Giusto M, Melandro F, Ginanni Corradini S, Mennini G, Berloco PB, Rossi M. Graft macrosteatosis and time of T-tube removal as risk factors for biliary strictures after liver transplantation. Clin Transplant. 2013 May;27(3):E332-8. doi: 10.1111/ctr.12124. Epub 2013 May 6.
• 2013
Melandro F, Lai Q, Levi Sandri GB, Guglielmo N, Di Laudo M, Morabito V, Pretagostini R, Berloco PB, Rossi M. A case of portal vein arterialization after a liver transplant. Exp Clin Transplant. 2013 Jun;11(3):287-9.
• 2013
Berloco PB, Levi Sandri GB, Guglielmo N, Lai Q, Melandro F, Poli L, Mennini G, Di Pierro GB, Gentile V, Rossi M. Bilateral ex vivo repair and kidney autotransplantation for complex renal artery aneurysms: A case report and literature review. Int J Urol. 2013 Jul 10. doi: 10.1111/iju.12224.
• 2013
Giannelli V, Rossi M, Giusto M, Lucidi C, Lattanzi B, Ruffa A, Ginanni Corradini S, Mennini G, Melandro F, Lai Q, Berloco P, Merli M. Conversion from twice-daily to once-daily Tacrolimus administration in liver transplant patient: results of long term follow-up. Eur Rev Med Pharmacol Sci. 2013 Oct;17(20):2718-20.
• 2013
Ginanni Corradini S, Siciliano M, Parlati L, Molinaro A, Cantafora A, Poli E, Mennini G, Melandro F, Vestri AR, Merli M, Bianco P, Corsi A, Toniutto P, Bitetto D, Falleti E, Attili AF, Berloco P, Rossi M. Recipient perioperative cholesterolaemia and graft cholesterol metabolism gene expression predict liver transplant outcome. Liver Int. 2013 Oct 6. doi: 10.1111/liv.12351.
• 2013
Cardinale V, Bragazzi MC, Carpino G, Torrice A, Fraveto A, Gentile R, Pasqualino V, Melandro F, Aliberti C, Bastianelli C, Brunelli R, Berloco PB, Gaudio E, Alvaro D. Cholangiocarcinoma: increasing burden of classifications. Hepatobiliary Surg Nutr. 2013 Oct;2(5):272-80. doi: 10.3978/j.issn.2304-3881.2013.10.02. Review.
• 2013
Lai Q, Nudo F, Mennini G, Spoletini G, Morabito V, Levi SG, Melandro F, Guglielmo N, Berloco PB, Rossi M. Expanded criteria for hepatocellular carcinoma after liver transplantation: a 20-year evolution.
Hepatogastroenterology. 2013 Nov-Dec;60(128):2039-41.
• 2014
Melandro F, Guglielmo N, Nudo F, Pretagostini R, Mennini G, Poli L, Giannakakis K, Berloco PB.
Renal Papillary Carcinoma Developed in a Kidney Transplant Recipient With Late IgA-Nephropathy
Exp Clin Transplant. 2014 Sep 3. doi: 10.6002/ect.2014.0124. [Epub ahead of print]
PMID: 25184211 [PubMed - as supplied by publisher]
• 2014
Lai Q, Spoletini G, Pinheiro RS, Melandro F, Guglielmo N, Lerut J.
From portal to splanchnic venous thrombosis: What surgeons should bear in mind.
World J Hepatol. 2014 Aug 27;6(8):549-58. doi: 10.4254/wjh.v6.i8.549. Review.
• 2014
Morabito V, Guglielmo N, Melandro F, Mazzesi G, Alesini F, Bosco S, Berloco PB.
Adult Wilms tumor: Case report.
Int J Surg Case Rep. 2015;6C:273-6. doi: 10.1016/j.ijscr.2014.06.021. Epub 2014 Dec 8..
• 2015
Guglielmo N, Melandro F, Poli L, Mennini G, Berloco PB, Rossi M.
Diaphragmatic hernia as a spontaneous sequela of a surgically-treated left infiltrating renal tumor: a case report.
Clin Ter. 2015;166(2):62-4. doi: 10.7417/CT.2015.1816.
• 2015
Guglielmo N, Melandro F, Improta L, Mennini G, Rossi D, Assenza M, Rossi M, Berloco PB.
Early right hepatectomy for severe liver trauma: a case report.
Clin Ter. 2015;166(2):e108-10. doi: 10.7417/T.2015.1830.
• 2015
Guglielmo N, Montalto GM, Della Pietra F, Garofalo M, Mennini G, Melandro F, Berloco PB.
Spontaneous Bilateral Adrenal Haemorrhage after Duodenopancreatectomy: a case report.
Clin Ter. 2015;166(2):e111-3. doi: 10.7417/T.2015.1831.
• 2015
Guglielmo N, Levi Sandri GB, Melandro F, Garofalo M, Poli L, Berloco PB
Cerebral Lymphoma in a Kidney Transplant: A Case Report.
Exp Clin Transplant. 2015 May 30. doi: 10.6002/ect.2014.0086.
• 2015
Guglielmo N, Melandro F, Montalto G, Poli L, Rossi FD, Mazzesi G, Berloco P.
Surgical treatment of renal carcinoma with atrial tumor thrombus avoiding cardiopulmonary bypass: step-by-step description.
Urologia. 2015 Jun 10;0(0):0. doi: 10.5301/uro.5000126.
• 2016
Guglielmo N, Melandro F, Nudo F, Mennini G, Levi Sandri GB, Berloco PB, Rossi M.
Chylous Leakage After a Laparoscopic Live-Donor Nephrectomy: Case Report and Literature Review.
Exp Clin Transplant. 2015 Sep 4. doi: 10.6002/ect.2014.0123.
• 2016
Di Martino M, Rossi M, Mennini G, Melandro F, Anzidei M, De Vizio S, Koryukova K, Catalano C.
Imaging follow-up after Liver Transplantation. Br J Radiol. 2016 May 18:20151025.
• 2017
Nevi L, Carpino G, Costantini D.,Cardinale V., Riccioni O., Di Matteo S., Melandro F., Berloco P. B., Reid L., Gaudio E. and Domenico Alvaro.
Hyaluronan coating improves liver engraftment of transplanted human biliary tree stem/progenitor cells.
Stem Cell Research & Therapy Stem Cell Res Ther. 2017 Mar 20;8(1):68
• 2017
Pretagostini R., Poli L., Lai Q., Russo G.,Nudo F.,Garofalo M.,Melandro F., Gaeta A., Nazzari C, Fazio C,Di Simone E., Vullo V., Berloco PB.
Pre-Emptive Therapy For The Treatment Of Cytomegalovirus After Kidney Transplantation.
Transplantation Proceedings, Transplant Proc. 2017 May;49(4):638-641
• 2017
Lai Q.,Melandro F., Rossi M. Hybrid partial alpps: a feasible approach in case of right trisegmentectomy and macrovascular invasion. Annals of Surgery. 2017 Mar 10
• 2017
Cavaggioni G, Poli E, Ferri F, Parlati L, Monaco V, Melcore C, Lattanzi B, Merli M, Mennini G, Melandro F, Rossi M, Ginanni Corradini S. MELDNa score is associated with psychopathology and reduced quality of life in cirrhotic patients with a liver transplant perspective. Metab Brain Dis. 2017 Jun;32(3):923-933
• 2017
Nevi L, Cardinale V, Carpino G, Costantini D, Di Matteo S, Cantafora A, Melandro F, Brunelli R, Bastianelli C, Aliberti C, Monti M, Bosco D, Berloco PB, Panici PB, Reid L, Gaudio E, Alvaro D.
Cryopreservation protocol for human biliary tree stem/progenitors, hepatic and pancreatic precursors. Sci Rep. 2017 Jul 20;7(1):6080.
• 2018
Mascagni P, Melandro F, Larghi Laureiro Z, Mennini G, Rossi M. Spontaneous hepatic rupture in a bodybuilder: a case report and review of the literature. Rev Esp Enferm Dig. 2018 Jan 9;110. doi: 10.17235/reed.2017.5103/2017. [Epub ahead of print]
• 2017
Lai Q, Vitale A, Iesari S, Finkenstedt A, Mennini G, Spoletini G, Hoppe-Lotichius M, Vennarecci G, Manzia TM, Nicolini D, Avolio AW, Frigo AC, Graziadei I, Rossi M, Tsochatzis E, Otto G, Ettorre GM, Tisone G, Vivarelli M, Agnes S, Cillo U, Lerut JIntention-to-treat survival benefit of liver transplantation in patients with hepatocellular cancer.
; European Hepatocellular Cancer Liver Transplant Study Group. Hepatology. 2017 Dec;66(6):1910-1919. doi: 10.1002/hep.29342. Epub 2017 Nov 6. Collaborating Author
• 2017
Cucchetti A, D'Amico G, Trevisani F, Morelli MC, Vitale A, Pinna AD, Cescon M Effect of direct-acting antivirals on future occurrence of hepatocellular carcinoma in compensated cirrhotic patients.; from the Special Interest Group on Hepatocellular carcinoma and new anti HCV therapies of the Italian Association for the Study of the Liver (AISF). Dig Liver Dis. 2017 Oct 18. pii: S1590-8658(17)31255-0. doi: 10.1016/j.dld.2017.10.004. [Epub ahead of print]Collaborating Author
• 2017
Fiacco F, Melandro F, Umbro I, Zavatto A, Cappoli A, Poli E, Ginanni Corradini S, Merli M, Tinti F, Nofroni I, Berloco PB, Rossi M, Mitterhofer AP.
Fluctuations of Estimated Glomerular Filtration Rate Outside Kidney Disease Improving Global Outcomes Diagnostic Criteria for Acute Kidney Injury in End-Stage Liver Disease Outpatients and Outcome Postliver Transplantation.
Transplant Direct. 2017 Oct 10;4(1):e222. doi: 10.1097/TXD.0000000000000733. eCollection 2018 Jan.
• 2018
Lai Q, Melandro F, Larghi Laureiro Z, Giovanardi F, Ginanni Corradini S, Ferri F, Hassan R, Rossi M, Mennini G
Platelet-to-lymphocyte ratio in the setting of liver transplantation for hepatocellular cancer: A systematic review and meta-analysis.
World J Gastroenterol. 2018 Apr 21;24(15):1658-1665. doi: 10.3748/wjg.v24.i15.1658.
• 2018
Giovanardi F, Lai Q, Garofalo M, Arroyo Murillo GA, Choppin de Janvry E, Hassan R, Larghi Laureiro Z, Consolo A, Melandro F, Berloco PB.
Collaterals management during pancreatoduodenectomy in patients with celiac axis stenosis: A systematic review of the literature.
Pancreatology. 2018 May 15. pii: S1424-3903(18)30087-5. doi: 10.1016/j.pan.2018.05.003. [Epub ahead of print] Review.
• 2018
Lai Q, Giovanardi F, Melandro F, Larghi Laureiro Z, Merli M, Lattanzi B, Hassan R, Rossi M, Mennini G.
Donor-to-recipient gender match in liver transplantation: A systematic review and meta-analysis.
World J Gastroenterol. 2018 May 28;24(20):2203-2210. doi: 10.3748/wjg.v24.i20.2203.
• 2018
Lai Q, Melandro F, Rossi M, Ruberto F, Pugliese F, Mennini G.
Role of perfusion machines in the setting of clinical liver transplantation: A qualitative systematic review.
Clin Transplant. 2018 Jun 6:e13310. doi: 10.1111/ctr.13310. [Epub ahead of print] Review.
• 2018
Schinzari V, Timperi E, Pecora G, Palmucci F, Gallerano D, Grimaldi A, Covino DA, Guglielmo N, Melandro F, Manzi E, Sagnotta A, Lancellotti F, Sacco L, Chirletti P, Grazi GL, Rossi M, Barnaba V.
Wnt3a/β-Catenin Signaling Conditions Differentiation of Partially Exhausted T-effector Cells in Human Cancers.
Cancer Immunol Res. 2018 Aug;6(8):941-952. doi: 10.1158/2326-6066.CIR-17-0712. Epub 2018 Jul 17.
• 2018
Guarino M, Viganò L, Ponziani FR, Giannini EG, Lai Q, Morisco F Recurrence of hepatocellular carcinoma after direct acting antiviral treatment for hepatitis C virus infection: Literature review and risk analysis.
;Special Interest Group on Hepatocellular carcinoma and new anti-HCV therapies” of the Italian Association for the Study of the Liver.
Dig Liver Dis. 2018 Aug 11. pii: S1590-8658(18)30880-6. doi: 10.1016/j.dld.2018.08.001. [Epub ahead of print] Review. Collaborating Author
• 2019
Giovanardi F, Nudo F, Lai Q, Garofalo M, Consolo A, Choppin De Janvry E, Arroyo Murillo GA, Ursi P, Stabile D, Melandro F, Berloco PB, Pretagostini R, Poli L.
Surgical Technique Notes of Arterial Vascular Reconstruction During Kidney Transplantation: Personal Experience and Literature Review.
Transplant Proc. 2019 Jan - Feb;51(1):128-131. doi: 10.1016/j.transproceed.2018.04.072. Epub 2018 Jun 28.
• 2019
Di Matteo S, Nevi L, Costantini D, Overi D, Carpino G, Safarikia S, Giulitti F, Napoletano C, Manzi E, De Rose AM, Melandro F, Bragazzi M, Berloco PB, Giuliante F, Grazi G, Giorgi A, Cardinale V, Adorini L, Gaudio E, Alvaro D.
The FXR agonist obeticholic acid inhibits the cancerogenic potential of human cholangiocarcinoma.
PLoS One. 2019 Jan 24;14(1):e0210077. doi: 10.1371/journal.pone.0210077. eCollection 2019.
• 2019
Lai Q, Melandro F, Mennini G, Rossi M.
New insights in the management of the middle hepatic vein dilemma.
Hepatobiliary Pancreat Dis Int. 2019 Feb 1. pii: S1499-3872(19)30027-X. doi: 10.1016/j.hbpd.2019.01.008.
• 2019
Caruso C, Pinter E, Poli E, Ferri F, Merli M, Colantuono S, Mennini G, Melandro F, Rumi G, Galandrini R, Ginanni Corradini S.
Acquired cow's milk sensitization after liver transplant in an adult: "clinical implications" and future strategies.
Allergy Asthma Clin Immunol. 2019 Feb 21;15:11. doi: 10.1186/s13223-019-0326-5. eCollection 2019.
• 2019
Costantini D, Overi D, Casadei L, Cardinale V, Nevi L, Carpino G, Di Matteo S, Safarikia S, Valerio M, Melandro F, Bizzarri M, Manetti C, Berloco PB, Gaudio E, Alvaro D.
Simulated microgravity promotes the formation of tridimensional cultures and stimulates pluripotency and a glycolytic metabolism in human hepatic and biliary tree stem/progenitor cells.
Sci Rep. 2019 Apr 3;9(1):5559. doi: 10.1038/s41598-019-41908-5.
• 2019
Lai Q, Vitale A, Iesari S, Finkenstedt A, Mennini G, Onali S, Hoppe-Lotichius M, Manzia TM, Nicolini D, Avolio AW, Mrzljak A, Kocman B, Agnes S, Vivarelli M, Tisone G, Otto G, Tsochatzis E, Rossi M, Viveiros A, Ciccarelli O, Cillo U, Lerut J; European Hepatocellular Cancer Liver Transplant Study Group.
The intention-to-treat effect of bridging treatments in the setting of Milan Criteria-IN patients waiting for liver transplantation.
Liver Transpl. 2019 May 14. doi: 10.1002/lt.25492. [Epub ahead of print] Collaborating Author
• 2019
Ferri F, Lai Q, Molinaro A, Poli E, Parlati L, Lattanzi B, Mennini G, Melandro F, Pugliese F, Maldarelli F, Corsi A, Riminucci M, Merli M, Rossi M, Ginanni Corradini S.
Donor Small-Droplet Macrovesicular Steatosis Affects Liver Transplant Outcome in HCV-Negative Recipients.
Can J Gastroenterol Hepatol. 2019 May 2;2019:5862985. doi: 10.1155/2019/5862985. eCollection 2019
• 2019
Melandro F, Giovanardi F, Hassan R, Larghi Laureiro Z, Ferri F, Rossi M, Mennini G, Pawlik TM, Lai Q.
Minimally Invasive Approach in the Setting of ALPPS Procedure: a Systematic Review of the Literature.
J Gastrointest Surg. 2019 Jun 13. doi: 10.1007/s11605-018-04092-x. [Epub ahead of print]
• 2019
Lai Q, Ruberto F, Melandro F, Larghi Laureiro Z, Rossi M, Mennini G.
Hypothermic oxygenated perfusion for a steatotic liver graft.
Hepatobiliary Pancreat Dis Int. 2019 Jun 11. pii: S1499-3872(19)30122-5. doi: 10.1016/j.hbpd.2019.05.012
• 2019
Lai Q, de Giacomo T, Consolo A, Castrovillari M, Melandro F, Cerbelli B, Pernazza A, Berloco PB, d'Amati G, Francioni F.
Esophageal carcinoma cuniculatum: systematic review of the literature and report of two cases.
Pathol Res Pract. 2019 Aug 17:152602. doi: 10.1016/j.prp.2019.152602. [Epub ahead of print] Review.
• 2019
Lai Q, Vitale A, Manzia TM, Foschi FG, Levi Sandri GB, Gambato M, Melandro F, Russo FP, Miele L, Viganò L, Burra P, Giannini EG;
Platelets and Hepatocellular Cancer: Bridging the Bench to the Clinics.
Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group.
Cancers (Basel). 2019 Oct 15;11(10). pii: E1568. doi: 10.3390/cancers11101568. Review.
• 2019
Giannini EG, Aglitti A, Borzio M, Gambato M, Guarino M, Iavarone M, Lai Q, Levi Sandri GB, Melandro F, Morisco F, Ponziani FR, Rendina M, Russo FP, Sacco R, Viganò M, Vitale A, Trevisani F
Overview of Immune Checkpoint Inhibitors Therapy for Hepatocellular Carcinoma, and The ITA.LI.CA Cohort Derived Estimate of Amenability Rate to Immune Checkpoint Inhibitors in Clinical Practice. Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group.
• 2019
Carpino G, Overi D, Melandro F, Grimaldi A, Cardinale V, Di Matteo S, Mennini G, Rossi M, Alvaro D, Barnaba V, Gaudio E, Mancone C.
Matrisome analysis of intrahepatic cholangiocarcinoma unveils a peculiar cancer-associated extracellular matrix structure.
Clin Proteomics. 2019 Oct 30;16:37. doi: 10.1186/s12014-019-9257-x. eCollection 2019.
• 2019
Nevi L, Costantini D, Safarikia S, Di Matteo S, Melandro F, Berloco PB, Cardinale V.
Cholest-4,6-Dien-3-One Promote Epithelial-To-Mesenchymal Transition (EMT) in Biliary Tree Stem/Progenitor Cell Cultures In Vitro.
Cells. 2019 Nov 15;8(11). pii: E1443. doi: 10.3390/cells8111443.
• 2019
Tinti F, Melandro F, Umbro I, Fiacco F, Zavatto A, Ginanni Corradini S, Lai S, Berloco PB, Rossi M, Mitterhofer AP.
Female gender and overestimation of glomerular filtration rate: Independent predictors of acute kidney injury after liver transplantation
.
Clin Nephrol. 2020 Feb;93(2):92-98. doi: 10.5414/CN109899.
• 2020
Ghinolfi D, Lai Q, Dondossola D, De Carlis R, Zanierato M, Patrono D, Baroni S, Bassi D, Ferla F, Lauterio A, Lazzeri C, Magistri P, Melandro F, Pagano D, Pezzati D, Ravaioli M, Rreka E, Toti L, Zanella A, Burra P, Petta S, Rossi M, Dutkowski P, Jassem W, Muiesan P, Quintini C, Selzner M, Cillo U.
Machine perfusions in liver transplantation: The evidence-based position paper of the italian society of organ and tissue transplantation.
Liver Transpl. 2020 Jun 10. doi: 10.1002/lt.25817. Online ahead of print.
• 2020
De Simone P, Melandro F, Balzano E, Tincani G, Catalano G, Ghinolfi D, Ducci J, Carrai P, Petruccelli S, Biancofiore G.
Coronavirus Disease 2019 Infection Requires Strengthening of the Chronic Care Model: The Impact on Liver Transplant Practice at a High-Volume Center in Italy.
Liver Transpl. 2020 Oct;26(10):1351-1353. doi: 10.1002/lt.25821. Epub 2020 Aug 25.
• 2020
Lai Q, Melandro F, Nowak G, Nicolini D, Iesari S, Fasolo E, Mennini G, Romano A, Mocchegiani F, Ackenine K, Polacco M, Marinelli L, Ciccarelli O, Zanus G, Vivarelli M, Cillo U, Rossi M, Ericzon BG, Lerut J.
The role of the comprehensive complication index for the prediction of survival after liver transplantation.
Updates Surg. 2020 Sep 6. doi: 10.1007/s13304-020-00878-4. Online ahead of print.
• 2020
Nevi L, Di Matteo S, Carpino G, Zizzari I, Safarikia S, Ambrosino V, Costantini D, Overi D, Giancotti A, Monti M, Bosco D, De Peppo V, Oddi A, De Rose AM, Melandro F, Bragazzi MC, Faccioli J, Massironi S, Grazi GL, Panici PB, Berloco PB, Giuliante F, Cardinale V, Invernizzi P, Caretti G, Gaudio E, Alvaro D.
DCLK1, a putative novel stem cell marker in human cholangiocarcinoma.
Hepatology. 2020 Sep 25. doi: 10.1002/hep.31571. Online ahead of print.
• 2020
Melandro F, Ghinolfi D, Balzano E, Tincani G, Catalano G, Biancofiore G, Peris A, De Simone P.
Transpl Int. 2020 Oct 8. doi: 10.1111/tri.13764. Online ahead of print.
Light at the end of the tunnel: COVID-19 lockdown has not halted liver transplantation at a high volume center in Italy.
• 2021
Melandro F, De Simone P, Ghinolfi D.
Viability testing during normothermic machine perfusion requires both hepatocellular and cholangiocellular criteria.
Updates Surg. 2021 Apr;73(2):781-783. doi: 10.1007/s13304-021-00976-x. Epub 2021 Jan 21
• 2021
Di Matteo S, Nevi L, Overi D, Landolina N, Faccioli J, Giulitti F, Napoletano C, Oddi A, Marziani AM, Costantini D, De Rose AM, Melandro F, Bragazzi MC, Grazi GL, Berloco PB, Giuliante F, Donato G, Moretta L, Carpino G, Cardinale V, Gaudio E, Alvaro D.
Metformin exerts anti-cancerogenic effects and reverses epithelial-to-mesenchymal transition trait in primary human intrahepatic cholangiocarcinoma cells.
Sci Rep. 2021 Jan 28;11(1):2557. doi: 10.1038/s41598-021-81172-0.
• 2021
Visseren T, Erler NS, Polak WG, Adam R, Karam V, Vondran FWR, Ericzon BG, Thorburn D, IJzermans JNM, Paul A, van der Heide F, Taimr P, Nemec P, Pirenne J, Romagnoli R, Metselaar HJ, Darwish Murad S; European Liver and Intestine Transplantation Association (ELITA). Collaborating Author
Recurrence of primary sclerosing cholangitis after liver transplantation - analysing the European Liver Transplant Registry and beyond.
Transpl Int. 2021 May 24. doi: 10.1111/tri.13925.
• 2021
Melandro F, Peris A, Lazzeri C, Migliaccio ML, De Simone P, Ghinolfi D.
Liver viability using normothermic regional perfusion in uncontrolled donation after circulatory death deserves a multi-parametric assessment.
Clin Transplant. 2021 Jul 14. doi: 10.1111/ctr.14428.
• 2021
Ghinolfi D, Melandro F, Torri F, Martinelli C, Cappello V, Babboni S, Silvestrini B, De Simone P, Basta G, Del Turco S.
Extended criteria grafts and emerging therapeutics strategy in liver transplantation. The unstable balance between damage and repair.
Transplant Rev (Orlando). 2021 Jul 16;35(4):100639. doi: 10.1016/j.trre.2021.100639.
• 2021
Melandro F, Del Turco S, Ghinolfi D.
Age disparities in transplantation.
Curr Opin Organ Transplant. 2021 Oct 1;26(5):536-541. doi: 10.1097/MOT.0000000000000906.
• 2021
Patrono D, Cussa D, Rigo F, Romagnoli R; Liver Machine Perfusion Survey Group.
Heterogeneous indications and the need for viability assessment: An international survey on the use of machine perfusion in liver transplantation.
Artif Organs. 2021 Aug 30. doi: 10.1111/aor.14061. Online ahead of print.
• 2021
Balzano E, Bernardi L, Tincani G, Ghinolfi D, Melandro F, Bronzoni J, Meli S, Arenga G, Biancofiore G, Crocetti L, De Simone P.
Implementing a robotic liver resection program does not always require prior laparoscopic experience.
Surg Endosc. 2021 Oct 4. doi: 10.1007/s00464-021-08645-1. Online ahead of print.
• 2021
Ghinolfi D, Lai Q, Carrai P, Petruccelli S, Morelli M, Melandro F, Biancofiore G, De Simone P.The impact of hepatitis C virus direct acting agents in liver transplant using very old donor grafts: a real-world single-center analysis.
Updates Surg. 2021 Nov 22. doi: 10.1007/s13304-021-01204-2. Online ahead of print.
• 2022
Del Turco S, Cappello V, Tapeinos C, Moscardini A, Sabatino L, Battaglini M, Melandro F, Torri F, Martinelli C, Babboni S, Silvestrini B, Morganti R, Gemmi M, De Simone P, Martins PN, Crocetti L, Peris A, Campani D, Basta G, Ciofani G, Ghinolfi D.
Cerium oxide nanoparticles administration during machine perfusion of discarded human livers: a pilot study.
Liver Transpl. 2022 Jan 31. doi: 10.1002/lt.26421.
• 2021
G Tiseo, R Fais, A Forniti, F Melandro, A. Tavanti, E. Ghelardi, P. De Simone, Marco Falcone, Antonella Lupetti Fatal fungemia by biofilm-producing Trichosporon asahii in a liver transplant candidate; Le Infezioni in Medicina, n. 3, 464-468, 2021
• 2022
Lai Q, Ghinolfi D, Avolio AW, Manzia TM, Mennini G, Melandro F, Frongillo F, Pellicciaro M, Larghi Laureiro Z, Aglietti R, Franco A, Quaranta C, Tisone G, Agnes S, Rossi M, de Simone P.
Proposal and validation of a liver graft discard score for liver transplantation from deceased donors: a multicenter Italian study.
Updates Surg. 2022 Mar 11. doi: 10.1007/s13304-022-01262-0.
• 2022
Melandro F, Basta G, Torri F, Biancofiore G, Del Turco S, Orlando F, Guarracino F, Maremmani P, Lazzeri C, Peris A, De Simone P, Ghinolfi D.
Normothermic regional perfusion in liver transplantation from donation after cardiocirculatory death: Technical, biochemical, and regulatory aspects and review of literature.
Artif Organs. 2022 Sep;46(9):1727-1740. doi: 10.1111/aor.14330. Epub 2022 Jun 22.
• 2022
Guarino M, Cossiga V, Capasso M, Mazzarelli C, Pelizzaro F, Sacco R, Russo FP, Vitale A, Trevisani F, Cabibbo G; The Associazione Italiana Per Lo Studio Del Fegato AISF HCC Special Interest Group.
Impact of SARS-CoV-2 Pandemic on the Management of Patients with Hepatocellular Carcinoma.
J Clin Med. 2022 Jul 31;11(15):4475. doi: 10.3390/jcm11154475. Collaborating author
• 2022
The role of antiplatelet therapies on incidence and mortality of hepatocellular carcinoma.
Lai Q, De Matthaeis N, Finotti M, Galati G, Marrone G, Melandro F, Morisco F, Nicolini D, Pravisani R, Giannini EG; Associazione Italiana per lo Studio del Fegato (AISF) HCC Special Interest Group.
Eur J Clin Invest. 2022 Sep 8:e13870. doi: 10.1111/eci.13870.
• 2022
Ghinolfi D, Melandro F, Patrono D, Lai Q, De Carlis R, Camagni S, Gambella A, Ruberto F, De Simone P.
A new ex-situ machine perfusion device. A preliminary evaluation using a model of donors after circulatory death pig livers.
Artif Organs. 2022 Jul 4. doi: 10.1111/aor.14351.
• 2022
Melandro F, Ghinolfi D, Lai Q.
Perfusate Enzymes and Platelets Indicate Early Allograft Dysfunction After Transplantation of Normothermically Preserved Livers.
Transplantation. 2022 Nov 1;106(11):e499-e500. doi: 10.1097/TP.0000000000004309.
• 2022
Melandro F, De Carlis R, Torri F, Lauterio A, De Simone P, De Carlis L, Ghinolfi D.
Viability Criteria during Liver Ex-Situ Normothermic and Hypothermic Perfusion.
Medicina (Kaunas). 2022 Oct 11;58(10):1434. doi: 10.3390/medicina58101434.
• 2023
Ghinolfi D, Melandro F, Torri F, Esposito M, Bindi M, Biancofiore G, Basta G, Del Turco S, Lazzeri C, Rotondo MI, Peris A, De Simone P.
The role of sequential normothermic regional perfusion and end-ischemic normothermic machine perfusion in liver transplantation from very extended uncontrolled donation after cardiocirculatory death.
Artif Organs. 2023 Feb;47(2):432-440. doi: 10.1111/aor.14468. Epub 2022 Dec 3.
• 2023
Ghinolfi D, Melandro F, Martins PN.
Knowledge and irreversibility of cell death: "Nought may endure but mutability".
Artif Organs. 2023 Feb;47(2):243-245. doi: 10.1111/aor.14476. Epub 2022 Dec 12.
• 2022
Pescarissi C, Penzo B, Ghinolfi D, Lai Q, Bindi L, DeCarlis R, Melandro F, Balzano E, DeSimone P, DeCarlis L, DeGasperi A; Italian Collaborative Group on Liver Transplantation from Extended Criteria Donation; Biancofiore GL.
The perioperative period of liver transplantation from unconventional extended criteria donors: data from two high-volume centres.
BMC Anesthesiol. 2022 Dec 15;22(1):390. doi: 10.1186/s12871-022-01932-x.
• 2023
Restructuring surgical training after COVID-19 pandemic: A nationwide survey on the Italian scenario on behalf of the Italian polyspecialistic young surgeons society (SPIGC).
Gallo G, Guaitoli E, Barra F, Picciariello A, Pasculli A, Coppola A, Pertile D, Meniconi RL; SPIGC Surgical Training Working Group.
Front Surg. 2023 Jan 11;9:1115653. doi: 10.3389/fsurg.2022.1115653. eCollection 2022.
Collaborating author
• 2023
Melandro F, Lai Q, Ghinolfi D, Manzia TM, Spoletini G, Rossi M, Agnes S, Tisone G, De Simone P.
Outcome of liver transplantation in elderly patients: an Italian multicenter case-control study.
Updates Surg. 2023 Feb 22. doi: 10.1007/s13304-023-01448-0.
• 2023
Basta G, Melandro F, Babboni S, Del Turco S, Ndreu R, Torri F, Martinelli C, Silvestrini B, Peris A, Lazzeri C, Guarracino F, Morganti R, Maremmani P, Bertini P, De Simone P, Ghinolfi D.
An extensive evaluation of hepatic markers of damage and regeneration in controlled and uncontrolled donation after circulatory death.
Liver Transpl. 2023 Mar 8. doi: 10.1097/LVT.0000000000000122.
• 2023
Quaresima S, Melandro F, Giovanardi F, Shah K, De Peppo V, Mennini G, Ghinolfi D, Limkemann A, Pawlik TM, Lai Q.
New Insights in the Setting of Transplant Oncology.
Medicina (Kaunas). 2023 Mar 14;59(3):568. doi: 10.3390/medicina59030568.
• 2023
Melandro F, Nasto RA, Ginesini M, Balzano E, Bindi ML, Ghinolfi D, Lai Q.
A narrative review of intrahepatic cholangiocarcinoma: a surgical curative option.
Chin Clin Oncol. 2023 Mar 27:cco-22-85. doi: 10.21037/cco-22-85.
• 2023
Ghinolfi D, Melandro F
Biliary anastomotic strictures are recipient, not donor-related complications; deserve international guidelines for clinical diagnosis and management.
.Indian J Gastroenterol. 2023 Apr 27. doi: 10.1007/s12664-022-01321-9.
• 2023
Parisse S, Gianoncelli A, Isani G, Gambaro FL, Andreani G, Malucelli E, Aquilanti G, Carlomagno I, Carletti R, Mischitelli M, Ferri F, Paterna V, Lai Q, Mennini G, Melandro F, Di Gioia C, Rossi M, Iotti S, Fratini M, Ginanni Corradini S.
Severity of Hepatocyte Damage and Prognosis in Cirrhotic Patients Correlate with Hepatocyte Magnesium Depletion.
Nutrients. 2023 Jun 3;15(11):2626. doi: 10.3390/nu15112626.
• 2023
Personalised management of patients with hepatocellular carcinoma: a multiparametric therapeutic hierarchy concept.
Vitale A, Cabibbo G, Iavarone M, Viganò L, Pinato DJ, Ponziani FR, Lai Q, Casadei-Gardini A, Celsa C, Galati G, Gambato M, Crocetti L, Renzulli M, Giannini EG, Farinati F, Trevisani F, Cillo U; HCC Special Interest Group of the Italian Association for the Study of the Liver.
Lancet Oncol. 2023 Jul;24(7):e312-e322. doi: 10.1016/S1470-2045(23)00186-9.
Collaborating author
• 2023
Liver transplantation with uncontrolled versus controlled DCD donors using normothermic regional perfusion and ex-situ machine perfusion.
Ghinolfi D, Patrono D, De Carlis R, Melandro F, Buscemi V, Farnesi F, Torri F, Lauterio A, Di Salvo M, Cerchione R, Zanierato M, Morganti R, Romagnoli R, De Simone P, De Carlis L.
Liver Transpl. 2023 Jul 17. doi: 10.1097/LVT.0000000000000219.
• 2023
Lai Q, Melandro F, Manzia TM, Spoletini G, Crovetto A, Gallo G, Hassan R, Mennini G, Angelico R, Avolio AW, Berrevoet F, Abreu de Carvalho L, Agnes S, Tisone G, Rossi M. The Role of Donor Gamma-Glutamyl Transferase as a Risk Factor for Early Graft Function after Liver Transplantation. J Clin Med. 2023 Jul 18;12(14):4744. doi: 10.3390/jcm12144744.
• 2023
Melandro, F.; Ghinolfi, D.; Gallo, G.; Quaresima, S.; Nasto, R.A.; Rossi, M.; Mennini, G.; Lai, Q. New Insights into Surgical Management of Intrahepatic Cholangiocarcinoma in the Era of “Transplant Oncology”. Gastroenterol. Insights 2023, 14, 406-419. https://doi.org/10.3390/gastroent14030030
• 2023
Siragusa L, Angelico R, Angrisani M, Zampogna B, Materazzo M, Sorge R, Giordano L, Meniconi R, Coppola A; SPIGC Survey Collaborative Group.
How future surgery will benefit from SARS-COV-2-related measures: a SPIGC survey conveying the perspective of Italian surgeons.
Updates Surg. 2023 Sep;75(6):1711-1727. doi: 10.1007/s13304-023-01613-5
• 2023
Balzano E, Bernardi L, Roesel R, Vagelli F, Ghinolfi D, Tincani G, Catalano G, Melandro F, Petrusic A, Popeskou SG, Christoforidis D, Majno-Hurst P, De Simone P, Cristaudi A.
Robotic versus laparoscopic liver resections: propensity-matched comparison of two-center experience.
Surg Endosc. 2023 Sep 18. doi: 10.1007/s00464-023-10358-6
• 2023
Melandro, F.; Ghinolfi, D.; Gallo, G.; Quaresima, S.; Nasto, R.A.; Rossi, M.; Mennini, G.; Lai, Q. New Insights into Surgical Management of Intrahepatic Cholangiocarcinoma in the Era of “Transplant Oncology”. Gastroenterol. Insights 2023, 14, 406-419. https://doi.org/10.3390/gastroent14030030
• 2023
Parisse S, Lai Q, Martini F, Martini A, Ferri F, Mischitelli M, Melandro F, Mennini G, Rossi M, Alvaro D, Ginanni Corradini S.
Rifaximin Reduces Risk of All-Cause Hospitalization in Cirrhotic Liver Transplant Candidates with Hepatic Encephalopathy.
J Clin Med. 2023 Oct 31;12(21):6871. doi: 10.3390/jcm12216871.
• 2024
Torri F, Balzano E, Melandro F, Maremmani P, Bertini P, Lo Pane P, Masini M, Rotondo MI, Babboni S, Del Turco S, Antonelli S, De Tata V, Biancofiore G, Guarracino F, Paolicchi A, De Simone P, Basta G, Ghinolfi D; DCDNet Study Group.
Sequential Normothermic Regional Perfusion and End-ischemic Ex Situ Machine Perfusion Allow the Safe Use of Very Old DCD Donors in Liver Transplantation.
Transplantation. 2024 Mar 12. doi: 10.1097/TP.0000000000004963
• 2024
Pravisani R, De Martino M, Mocchegiani F, Melandro F, Patrono D, Lauterio A, Di Francesco F, Ravaioli M, Zambelli MF, Bosio C, Dondossola D, Lai Q, Zanchetta M, Dingfelder J, Toti L, Iacomino A, Nicolae S, Ghinolfi D, Romagnoli R, De Carlis L, Gruttadauria S, Cescon M, Colledan M, Carraro A, Caccamo L, Vivarelli M, Rossi M, Nadalin S, Gyori G, Tisone G, Vennarecci G, Rostved A, De Simone P, Isola M, Baccarani U.
Recipient hepatectomy technique may affect oncological outcomes of Liver Transplantation for hepatocellular carcinoma.
Liver Transpl. 2024 Apr 1. doi: 10.1097/LVT.0000000000000373
• 2024
Lai Q, Parisse S, Ginanni Corradini S, Ferri F, Kolovou K, Campagna P, Melandro F, Mennini G, Merli M, Rossi M.
Evolution of transplant oncology indications: a single-institution experience over 40 years.
Updates Surg. 2024 Apr 8. doi: 10.1007/s13304-024-01827-1.
2025 Clinical aspects and controversies of spontaneous portosystemic shunts in cirrhotic patients.
Parisse S, Coltorti E, Ferri F, Melandro F, Corona M, Lucatelli P, Lai Q, Ginanni Corradini S.
Minerva Gastroenterol (Torino). 2025 Mar 19. doi: 10.23736/S2724-5985.25.03874-4. Online ahead of print.
2025 Pigment Epithelium-Derived Factor Inhibits Cell Motility and p-ERK1/2 Signaling in Intrahepatic Cholangiocarcinoma Cell Lines.
Porreca V, Corbella E, Palmisano B, Peres M, Angelone P, Barbagallo C, Stella M, Mignogna G, Mennini G, Melandro F, Rossi M, Ragusa M, Corsi A, Riminucci M, Maras B, Mancone C.
Biology (Basel). 2025 Feb 3;14(2):155. doi: 10.3390/biology14020155.
2025 The role of the comprehensive complication index in the prediction of tumor-related death in transplanted patients with hepatocellular carcinoma.
Lai Q, Melandro F, Vitale A, Ghinolfi D, Coubeau L, Pravisani R, Nowak G, Mocchegiani F, Vivarelli M, Rossi M, Ericzon BG, Baccarani U, De Simone P, Cillo U, Lerut J.
Updates Surg. 2025 Feb 10. doi: 10.1007/s13304-025-02101-8. Online ahead of print.
2025 Short (2-Hour) Non-Oxygenated End-Ischemic Hypothermic Perfusion Versus Cold Storage in the Setting of Renal Transplantation.
Ruberto F, Lai Q, Piazzolla M, Poli L, Zullino V, Diamantini G, Brisciani M, Giovanardi F, Melandro F, Quaresima S, Rossi M, Garofalo M, Pugliese F.
Artif Organs. 2025 May;49(5):831-841. doi: 10.1111/aor.14953. Epub 2025 Jan 24.
2025 Transjugular Intrahepatic Portosystemic Shunt as a Bridge to Abdominal Surgery in Cirrhosis.
Melandro F, Parisse S, Ginanni Corradini S, Cardinale V, Ferri F, Merli M, Alvaro D, Pugliese F, Rossi M, Mennini G, Lai Q.
J Clin Med. 2024 Apr 11;13(8):2213. doi: 10.3390/jcm13082213.
PMID: 38673486 Free PMC article. Review.
ATTIVITA' DIDATTICA
Docente Corso di Laurea A in infermieristica, Sapienza Università di Roma
Docente Corso di Laurea in Fisioterapia, Sapienza Università di Roma
Docente Corso di Laurea C in Medicina e Chirurgia, Sapienza Università di Roma
Docente Corso di Laurea B in Medicina e Chirurgia, Sapienza Università di Roma
Docente Corso di Laurea E in Medicina e Chirurgia, Sapienza Università di Roma
Docente Corso di Laurea HT in Medicina e Chirurgia, Sapienza Università di Roma
Docente Scuola di Specializzazione in Chirurgia Generale, Sapienza Università di Roma